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CompletedNCT00744094Updated Sep 23, 2015

Resistance Training in Elderly

A Phase 1/2 interventional study of protein drink and Resistance training in Sarcopenia, Atrophy and Aging, sponsored by Maastricht University Medical Center. Completed at 1 site in Netherlands. Open to male participants aged 65 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-09-23.

Sponsored by Maastricht University Medical Center · Phase 1/2, Interventional, and Treatment

Phase
Phase 1/2
Study type
Interventional
Enrollment
26
Allocation
Randomized
Ages
65 Years to 85 Years
Sex
Male
01

Study summary

In the present study the investigators aim to determine whether protein supplementation can augment the response to a 12 week resistance training program in healthy elderly men.

02

Conditions studied

  • Sarcopenia
  • Atrophy
  • Aging

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Keywords

  • resistance training
  • protein supplementation
  • hypertrophy
03

In context

Sarcopenia

1,208 studies on the registry are indexed under Sarcopenia; 402 are open to participants now.

This study's enrollment of 26 is below the median of 60 across 775 interventional studies indexed under Sarcopenia.

Browse Sarcopenia studies →

Lead sponsor

Maastricht University Medical Center is the lead sponsor of 835 studies on the registry; 121 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years to 85 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • Living independently

Exclusion criteria

Exclusion Criteria:

  • Diabetes
  • Cardiovascular disease
  • Orthopedic limitations
  • Any disorder known to compromise ability for resistance training
  • History of resistance training in past 5 years
05

Study design

Phase
Phase 1 / Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
26 participants (actual)

Study arms

  • Placebo comparator
    1

    placebo drink

    Behavioral: Resistance training

  • Experimental
    2

    protein drink

    Dietary Supplement: protein drink · Behavioral: Resistance training

Interventions

  • Dietary supplementprotein drink

    250 ml protein hydrolysate solution

  • BehavioralResistance training

    12 weeks resistance training, 3 days per week

06

What researchers measure

Primary outcomes

  1. Muscle mass measured at limb and cellular level

    Time frame: before and after 12 weeks of intervention

Secondary outcomes

  1. Muscle strength

    Time frame: before and after 12 weeks of intervention

  2. Body composition

    Time frame: before and after 12 weeks of intervention

07

Study locations

1 site
  • Maastricht University
    Maastricht, 6200MD, Netherlands
08

References and documents

Publications

  • Verdijk LB, Jonkers RA, Gleeson BG, Beelen M, Meijer K, Savelberg HH, Wodzig WK, Dendale P, van Loon LJ. Protein supplementation before and after exercise does not further augment skeletal muscle hypertrophy after resistance training in elderly men. Am J Clin Nutr. 2009 Feb;89(2):608-16. doi: 10.3945/ajcn.2008.26626. Epub 2008 Dec 23. PubMed 19106243 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 23, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00744094
Lead sponsor
Maastricht University Medical Center
Collaborators
The Anna Foundation, DSM Food Specialties
First posted
Aug 29, 2008
Start date
Jan 2007
Primary completion
Sep 2007
Completion
Jul 2008
Last update
Sep 23, 2015

Study contacts

Luc JC van Loon, PhD
principal investigator · Maastricht University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2008. You cannot join it, but the record below documents what was studied.

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