CompletedNCT00726245Updated Jul 12, 2011

Plasma Rich in Growth Factors (PRGF) Treatment for Muscle Tear

A Phase 2/3 interventional study of PRGF and Placebo in Muscle Tear, sponsored by Meir Medical Center. Completed at 1 site in Israel. Open to participants aged 15 Years to 40 Years. Per ClinicalTrials.gov, last updated 2011-07-12.

Sponsored by Meir Medical Center · Phase 2/3, Interventional, and Treatment

Phase: Phase 2/3
Study type: Interventional
Enrollment: 50
Allocation: Randomized
Ages: 15 Years to 40 Years
Sex: All

Study summary

the improvement of symptoms and disease progress by the treatment of OA of the knee with PRGF

Conditions studied

Muscle Tear

In context

Lead sponsor

Meir Medical Center is the lead sponsor of 389 studies on the registry; 34 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 15 Years to 40 Years
Sexes eligible: All
Accepts healthy volunteers: No

Inclusion criteria

US diagnosed muscle tear
age 15-40 years old

Exclusion criteria

Exclusion Criteria:

pregnancy
mental or physical disabilities

Study design

Phase: Phase 2 / Phase 3
Primary purpose: Treatment
Allocation: Randomized
Intervention model: Parallel assignment
Masking: Double (Participant, Outcomes assessor)
Enrollment: 50 participants (estimated)

Study arms

Experimental
1
PRGF
Biological: PRGF
Placebo comparator
2
physiological saline
Biological: Placebo

Interventions

BiologicalPRGF
3-6mg IM (to area of muscle tear)
BiologicalPlacebo
3cc IM of physiological saline

What researchers measure

Primary outcomes

improvement of symptoms / disease progress
Time frame: 1 year

Study locations

1 site

Meir Medicak Center
Kfar Saba, Israel

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Jul 12, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT00726245
Lead sponsor: Meir Medical Center
First posted: Jul 31, 2008
Start date: Jan 2008
Primary completion: Feb 2009
Completion: Mar 2011
Last update: Jul 12, 2011

Oversight

Data monitoring committee: Yes

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2011. You cannot join it, but the record below documents what was studied.

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Discussion

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