An interventional study of Manual removal and Expressed removal in Pregnancy and Cesarean Delivery, sponsored by Corewell Health East. Terminated at 1 site in United States. Open to female participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-07-16.
Sponsored by Corewell Health East · Not applicable, Interventional, and Treatment
The purpose of this study is to evaluate whether manual removal of the placenta during a cesarean delivery results in higher changes in the resistance of blood flow throughout the body, also called systemic vascular resistance (SVR)
Patients presenting to William Beaumont Hospital Royal Oak Labor and Delivery for a scheduled low transverse cesarean delivery will be asked to participate in a prospective, randomized study to evaluate any changes in systemic vascular resistance (SVR) pre- and post-delivery.
After obtaining informed consent, the patients will be randomized to one of two groups: group 1 will have manual removal of the placenta at cesarean section and group 2 will have expressed removal of the placenta at cesarean section.
Both groups will have a pre-operative continuous wave Doppler evaluation and a post-operative continuous wave Doppler evaluation at 24 hours after delivery. Continuous wave Doppler evaluation will be used pre- and post-operatively to evaluate any changes in SVR.
Corewell Health East is the lead sponsor of 19 studies on the registry; 9 are open to participants now.
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Exclusion Criteria:
Manual removal of placenta
Behavioral: Manual removal
expressed placental removal
Procedure: Expressed removal
Manual removal of placenta during cesarean delivery
Also known as: manual
Surgeon will perform an expressed delivery of the placenta
Also known as: expressed
Hemodynamic profile, especially Systemic Vascular Resistance
Time frame: immediately before and 24 hours after cesarean delivery
development of postpartum preeclampsia
Time frame: within 1 week of delivery
This study is terminated, as verified in Jul 2012. You cannot join it, but the record below documents what was studied.
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Corewell Health East