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CompletedNCT00679575Updated Dec 8, 2010

Statins and Risk of Myocardial Infarction in Real Life in France

An observational study in Myocardial Infarction, sponsored by AstraZeneca. Completed at 56 sites in France. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2010-12-08.

Sponsored by AstraZeneca · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
13,171
Ages
18 Years and older
Sex
All
01

Study summary

The main objective of this case-referent study is to assess the impact of statins usage on the risk of having a first myocardial infarction (MI) in a real life situation in France

02

Conditions studied

  • Myocardial Infarction

Keywords

  • statins
  • myocardial infarction
  • case-referent study
  • France
03

In context

Myocardial Infarction

2,744 studies on the registry are indexed under Myocardial Infarction; 418 are open to participants now.

This study's enrollment of 13,171 is above the median of 500 across 983 observational studies indexed under Myocardial Infarction.

Browse Myocardial Infarction studies →

Lead sponsor

AstraZeneca is the lead sponsor of 3,429 studies on the registry; 270 are open to participants now.

Of its 357 completed or terminated interventional studies of FDA-regulated products, 173 (48%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Cases : Patients recruited by a cardiologist in hospital / Referents : Patients recruited by a GP, community sample

Inclusion criteria

  • Patients can speak French or English
  • Patients can be interviewed by telephone
  • Place of usual residence in the area of recruitment

Exclusion criteria

Exclusion Criteria:

  • Patients refusing to participate in the study
  • Patients who cannot be reached by telephone
  • Previous history of myocardial infarction
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
13,171 participants (actual)

Groups and cohorts

  • 1

    Cases : Patients with a first myocardial infarction

  • 2

    Referents : Patients recruited by a GP during a routine consultation

06

What researchers measure

Primary outcomes

  1. Assess the impact of the different statins (molecules) usage on the risk of having a first myocardial infarction in a real life situation in France

    Time frame: in 2011

Secondary outcomes

  1. Assess the interaction between statin treatment and risk factors such as cholesterol, age, gender, tobacco, alcohol, co-prescriptions, co-morbidities

    Time frame: in 2011

  2. Assess the populational impact of statins usage on the risk of having a first myocardial infarction

    Time frame: in 2011

  3. Assess the risk of having a first myocardial infarction according to high and low dosages of statins

    Time frame: in 2011

07

Study locations

56 sites
  • Research Site
    Ambilly, France
  • Research Site
    Angers, France
  • Research Site
    Arles, France
  • Research Site
    Bagnols sur Ceze, France
  • Research Site
    Bayonne, France
  • Research Site
    Beziers, France
  • Research Site
    Boulogne sur mer, France
  • Research Site
    Bourgoin Jallieu, France
  • Research Site
    Bron, France
  • Research Site
    Cambo les Bains, France
  • Research Site
    Cenon, France
  • Research Site
    Chateauroux, France
  • Research Site
    Clermont Ferrand, France
  • Research Site
    Colmar, France
  • Research Site
    Crest, France
  • Research Site
    Dijon, France
  • Research Site
    Draguignan, France
  • Research Site
    Eaubonne, France
  • Research Site
    Firminy, France
  • Research Site
    Forbach, France
  • Research Site
    Frejus, France
  • Research Site
    Gleize, France
  • Research Site
    Grasse, France
  • Research Site
    Gueret, France
  • Research Site
    La Rochelle, France
  • Research Site
    Langres, France
  • Research Site
    Laon, France
  • Research Site
    Le Coudray, France
  • Research Site
    Le Mans, France
  • Research Site
    Le Puy en Velay, France
  • Research Site
    Mayenne, France
  • Research Site
    Millau, France
  • Research Site
    Montelimar, France
  • Research Site
    Montfermeil, France
  • Research Site
    Montpellier, France
  • Research Site
    Nimes, France
  • Research Site
    Orange, France
  • Research Site
    Orleans, France
  • Research Site
    Paris, France
  • Research Site
    Pau, France
  • Research Site
    Perpignan, France
  • Research Site
    Puilboreau, France
  • Research Site
    Rueil Malmaison, France
  • Research Site
    Rumilly, France
  • Research Site
    Saint Jean des Verges, France
  • Research Site
    Sallanches, France
  • Research Site
    Salon de provence, France
  • Research Site
    Sens, France
  • Research Site
    St Amand Monrond, France
  • Research Site
    St-Esteve, France
  • Research Site
    Thonon les Bains, France
  • Research Site
    Toulouse, France
  • Research Site
    Tours, France
  • Research Site
    Tulles, France
  • Research Site
    Valence, France
  • Research Site
    Villefranche de Rouergue, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 8, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00679575
Lead sponsor
AstraZeneca
First posted
May 19, 2008
Start date
Mar 2007
Primary completion
Nov 2010
Completion
Nov 2010
Last update
Dec 8, 2010

Study contacts

Lucien Abenhaim
study chair · LA-SER29, rue du Faubourg Saint-Jacques75014 Paris

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Dec 2010. You cannot join it, but the record below documents what was studied.

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