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CompletedNCT00660803Updated Jan 21, 2010

Retrospective Brazilian Study of Fulvestrant in Advanced Breast Cancer

An observational study in Breast Cancer, sponsored by AstraZeneca. Completed at 4 sites in Brazil. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-01-21.

Sponsored by AstraZeneca · Observational

Study type
Observational
Time perspective
Retrospective
Enrollment
200
Ages
18 Years and older
Sex
Female
01

Study summary

Characterize the demographic and clinical features, as well as the main treatment results, among patients with advanced breast cancer treated with fulvestrant in Brazil.

02

Conditions studied

  • Breast Cancer

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Keywords

  • Advanced Breast Cancer
  • Hormone Therapy
03

In context

Breast Neoplasms

12,544 studies on the registry are indexed under Breast Neoplasms; 2,892 are open to participants now.

This study's planned enrollment of 200 is close to the median of 184 across 2,642 observational studies indexed under Breast Neoplasms.

Browse Breast Neoplasms studies →

Lead sponsor

AstraZeneca is the lead sponsor of 3,429 studies on the registry; 270 are open to participants now.

Of its 357 completed or terminated interventional studies of FDA-regulated products, 173 (48%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

hospitals and primary care clinics

Inclusion criteria

  • Positive HR or ER by immunohistochemistry
  • Postmenopausal status at the time of treatment with fulvestrant
  • Failure of at least one previous endocrine therapy before treatment with fulvestrant.

Exclusion criteria

Exclusion Criteria:

  • Patients who are still undergoing treatment with fulvestrant will not be eligible to participate in the study
05

Study design

Time perspective
Retrospective
Enrollment
200 participants (estimated)

Groups and cohorts

  • 1

    Postmenopausal women with hormone-receptor positive, advanced breast cancer who have failed at least one previous endocrine therapy and who have been treated at any one of the participating centres with fulvestrant.

    Drug: Fulvestrant

Interventions

  • DrugFulvestrant

    Also known as: Faslodex

06

What researchers measure

Primary outcomes

  1. Time to tumour progression

  2. Objective response

Secondary outcomes

  1. Duration of treatment with fulvestrant

  2. Time and duration of response

  3. Overall survival

07

Study locations

4 sites
  • Research Site
    Recife, PE, Brazil
  • Research Site
    Rio de Janeiro, RJ, Brazil
  • Research Site
    Porto Alegre, RS, Brazil
  • Research Site
    Sao Paulo, SP, Brazil
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 21, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00660803
Lead sponsor
AstraZeneca
Collaborators
Dendrix - Scientific Information Architecture
First posted
Apr 17, 2008
Start date
May 2008
Primary completion
Apr 2009
Completion
Apr 2009
Last update
Jan 21, 2010

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2010. You cannot join it, but the record below documents what was studied.

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