CClinicalTrials.gg
Status unknownNCT00602186Updated Jan 29, 2008

Effect of Tamsulosin vs Prazosin in Treatment of Female Voiding Dysfunction

A Phase 1/2 interventional study of tamsolusin and prazosin in Neurogenic Bladder, sponsored by Tabriz University. Status unknown. Open to female participants aged 20 Years to 70 Years. Per ClinicalTrials.gov, last updated 2008-01-29.

Sponsored by Tabriz University · Phase 1/2, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jan 2008), so the status shown — last known as Active, not recruiting — may be out of date.
Phase
Phase 1/2
Study type
Interventional
Enrollment
80
Allocation
Randomized
Ages
20 Years to 70 Years
Sex
Female
01

Study summary

The purpose of this study is to determine whether Tamsolusin or Prazosin are effective in the treatment of female voiding dysfunction(BOO)

Read the detailed description

Voiding dysfunction is not uncommon in Tabriz.About 20% of patients in female urology clinic of Tabriz university of medical sciences sufered from some degrees of voiding dysfunction (due to bladder imparement or bladder outlet obstruction).There is limited information about medical treatment of those patients. On the other hand alpha adrenergic blockers are the first choice medication in BENIGN PROSTATIC HYPERPLASIA. There is some new facts about destribution of alpha adrenergic blockers in female pelvic floor.The purpose of this study is to comparision whether Tamsolusin 0.4/daily or Prazosin 1 mg/daily are effective in the treatment of female voiding dysfunction(BOO)

02

Conditions studied

  • Neurogenic Bladder

Keywords

  • female voiding dysfunction
  • Tamsolusin
  • prazosin
03

In context

Urinary Bladder, Neurogenic

185 studies on the registry are indexed under Urinary Bladder, Neurogenic; 40 are open to participants now.

This study's enrollment of 80 is above the median of 36 across 124 interventional studies indexed under Urinary Bladder, Neurogenic.

Browse Urinary Bladder, Neurogenic studies →

Lead sponsor

Tabriz University is the lead sponsor of 15 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 70 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Healthy females with voiding difficulty with MFR\<12 and post void residual urine>50cc

Exclusion criteria

Exclusion Criteria:

  • History of pelvic floor surgury during last 3 month
  • Any contraindication for Tamsolusin or prazosin
05

Study design

Phase
Phase 1 / Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
80 participants (actual)

Study arms

  • Experimental
    1

    taking Tamsulosin

    Drug: tamsolusin

  • Active comparator
    2

    taking prasosin

    Drug: prazosin

Interventions

  • Drugtamsolusin

    0.4 mg /day

    Also known as: Flomax

  • Drugprazosin

    1 mg/day

06

What researchers measure

Primary outcomes

  1. patient symptoms improvement(Standard questionare)

    Time frame: every month untile 3 months

Secondary outcomes

  1. Urodynamics parameters improvement

    Time frame: three months later

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 29, 2008, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00602186
Lead sponsor
Tabriz University
First posted
Jan 28, 2008
Start date
Jul 2005
Primary completion
Mar 2007 (estimated)
Completion
Mar 2008 (estimated)
Last update
Jan 29, 2008

Study contacts

SAKINEH hajebrahimi, MD
study director · Urology department ofTabriz University of Medical Sciences

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2008. You cannot join it, but the record below documents what was studied.

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