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TerminatedNCT00560846Updated Sep 5, 2013

Perioperative Nutrition in Upper Gastrointestinal (GI) Cancer Surgery

An interventional study of Impact and Glucose load in Stomach Neoplasms and Esophageal Neoplasms, sponsored by Dan Azagury. Terminated at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-09-05.

Sponsored by Dan Azagury · Not applicable, Interventional, and Treatment

Why this study was terminated
Insufficient recruitment over time.
Phase
Not applicable
Study type
Interventional
Enrollment
43
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this study is to demonstrate the influence of peri-operative nutrition on the post-operative complications, preservation of lean body mass and length of stay after gastrectomy or oesophagectomy.

02

Conditions studied

  • Stomach Neoplasms
  • Esophageal Neoplasms

Keywords

  • Gastric cancer
  • Esophageal cancer
  • Surgical complications
  • Immunonutrition
03

In context

Neoplasms

9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.

This study's enrollment of 43 is below the median of 50 across 7,253 interventional studies indexed under Neoplasms.

Browse Neoplasms studies →

Lead sponsor

This is the only study on the registry with Dan Azagury as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Surgery for Upper GI cancer
  • Age over 18
  • Informed consent

Exclusion criteria

Exclusion Criteria:

  • Major swallowing disorders
  • Dementia or other psychological state precluding compliance and understanding of research protocol
  • Pre-existing enteral or parenteral nutrition
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
43 participants (actual)

Study arms

  • Experimental
    Nutrition

    Pre-operative immunonutritrion, pre-operative glucose load, post-operative early immunonutrition

    Dietary Supplement: Impact · Dietary Supplement: Glucose load

  • No intervention
    Control

    No immunonutrition, no glucose load, no early enteral immunonutrition

Interventions

  • Dietary supplementImpact

    Preoperative 5 day oral Impact and early post-operative enteral Impact

  • Dietary supplementGlucose load

    Pre-operative glucose load: 800 ml of PreOp (Nutricia) 12 h before surgery; 400 ml of PreOp (Nutricia) 2 hours before surgery

    Also known as: PreOp Nutricia

06

What researchers measure

Primary outcomes

  1. Rate of post-operative complications

    Time frame: 30 days

  2. Length of stay

    Time frame: 30 days

Secondary outcomes

  1. Quality of life

    Time frame: 1 year

  2. Body composition

    Time frame: 1 year

07

Study locations

1 site
  • Hôpitaux Universitaires Genève
    Geneva, 1204, Switzerland
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 5, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00560846
Lead sponsor
Dan Azagury
Responsible party
Dan Azagury (Medecin adjoint du chef de service, University Hospital, Geneva) — Sponsor-investigator
First posted
Nov 20, 2007
Start date
Nov 2007
Primary completion
Sep 2012
Completion
Sep 2012
Last update
Sep 5, 2013

Study contacts

Dan E Azagury, MD
principal investigator · University Hospital, Geneva

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Sep 2013. You cannot join it, but the record below documents what was studied.

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