An interventional study of polyethylene glycol and Sodium phosphate in Colonoscopy, sponsored by Sheba Medical Center. Terminated at 1 site in Israel. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2018-06-14.
Sponsored by Sheba Medical Center · Not applicable, Interventional, and Treatment
The aim of the study is to compare the efficacy of Polyethylene glycol versus sodium phosphate as purgative for colon preparation to colonoscopy, after the failure of preparation with sodium phosphate for first colonoscopy. The hypothesis tested is whether there is advantage for substituting the purgative used, as compared to repeating the colonoscopy with the same purgative.Briefly, patients whose preparation was inadequate, will be allocated randomly to a group that will receive 3L Polyethylene glycol versus a group that will receive sodium phosphate(45ccX2). Both groups will be instructed to extend low-fiber diet to 5 days. Cleanliness of the colon at colonoscopy will be assessed blindly by an experienced endoscopist.
The aim of the study is to compare the efficacy of Polyethylene glycol versus sodium phosphate as purgative for colon preparation to colonoscopy, after the failure of preparation with sodium phosphate for first colonoscopy. The hypothesis tested is whether there is advantage for substituting the purgative used, as compared to repeating the colonoscopy with the same purgative.Briefly, the study will be composed of patients whose preparation was judged to be inadequate in a first colonoscopy by an endoscopist independent of the current study. They will be allocated randomly to a group that will receive 3L Polyethylene glycol versus a group that will receive sodium phosphate(45ccX2). Both groups will be instructed to extend low-fiber diet to 5 days. Cleanliness of the colon at colonoscopy will be assessed blindly by an experienced endoscopist.
Sheba Medical Center is the lead sponsor of 660 studies on the registry; 63 are open to participants now.
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Exclusion Criteria:
Ingestion of 3L polyethylene Glycol
Drug: polyethylene glycol
Ingestion of 2 doses of sodium phosphate 45 cc
Drug: Sodium phosphate
Single time 3 liters PEG, 250 cc every 15 minutes the day before colonoscopy
Also known as: Meroken New, Polyethylene glycol 3350, Taro, Israel
Sodium phosphate 45cc, 2 doses 4 hours apart the day before colonoscopy
Also known as: Sodium phosphate solution; Soffodex, Dexxon, Israel
Colon cleanliness at the second colonoscopy
Time frame: within 24 hours of purgative ingestion, and within 30 minutes of colonoscopy
Tolerability of purgative regimen
Time frame: within 24 hours of purgative ingestion
This study is terminated, as verified in Jun 2018. You cannot join it, but the record below documents what was studied.
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Sheba Medical Center