CClinicalTrials.gg
CompletedNCT00529919MuffinUpdated Sep 14, 2007

Effects of Medium Chain Triglyceride Oil, Versus Olive Oil, for Weight Loss

An interventional study of Weight loss in Overweight, sponsored by University of Alabama at Birmingham. Completed at 1 site in United States. Open to participants aged 19 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2007-09-14.

Sponsored by University of Alabama at Birmingham · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
53
Allocation
Randomized
Ages
19 Years to 50 Years
Sex
All
01

Study summary

The primary aim of this research project is to determine whether the incorporation of food products containing medium chain triglyceride (MCT) oil in a weight-loss program results in a different degree of weight-loss and total and regional fat mass loss than the incorporation of extra light olive oil. The secondary goals are to test whether there are differences in in metabolic risk profile changes between the 2 diets. We hypothesize that men and women who consumed MCT oil as part of their weight loss program will lose more weight and body fat than those who consume olive oil in their weight loss diet.

02

Conditions studied

  • Overweight

Keywords

  • Overweight
  • Obesity
  • Weight loss
  • Medium chain triglycerides
  • Cardiovascular disease risk
03

In context

Overweight

3,670 studies on the registry are indexed under Overweight; 850 are open to participants now.

This study's enrollment of 53 is below the median of 73 across 3,175 interventional studies indexed under Overweight.

Browse Overweight studies →

Lead sponsor

University of Alabama at Birmingham is the lead sponsor of 1,394 studies on the registry; 282 are open to participants now.

Of its 156 completed or terminated interventional studies of FDA-regulated products, 124 (79%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • body mass index 27-33 kg/m2
  • pre-menopausal women
  • weight stable for at least 6 months
  • normal score on Brief Symptoms Inventory questionnaire

Exclusion criteria

Exclusion Criteria:

  • chronic disease
  • weight loss treatment
  • medication known to affect body weight
  • unstable blood pressure, glucose, lipid levels
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Care provider)
Enrollment
53 participants (actual)

Study arms

  • Active comparator
    1

    MCT oil consumption

    Dietary Supplement: Weight loss

  • Placebo comparator
    2

    Olive oil consumption

    Dietary Supplement: Weight loss

Interventions

  • Dietary supplementWeight loss

    Weight loss study including consumption of either 22-25 g of medium chain triglyceride oil or olive oil

    Also known as: MCT oil, Neobee 1053, Stepan Company

06

What researchers measure

Primary outcomes

  1. Change in body weight and fat mass, change in plasma lipid concentrations, fasting glucose and fasting insulin

    Time frame: 16 weeks

Secondary outcomes

  1. Change in blood pressure, change in fat-free mass

    Time frame: 16 weeks

07

Study locations

1 site
  • University of Alabama at Birmingham
    Birmingham, Alabama 35294, United States
08

References and documents

Publications

  • St-Onge MP, Bosarge A, Goree LL, Darnell B. Medium chain triglyceride oil consumption as part of a weight loss diet does not lead to an adverse metabolic profile when compared to olive oil. J Am Coll Nutr. 2008 Oct;27(5):547-52. doi: 10.1080/07315724.2008.10719737. PubMed 18845704 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 14, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00529919
Lead sponsor
University of Alabama at Birmingham
Collaborators
International Life Sciences Institute
First posted
Sep 14, 2007
Start date
Mar 2005
Completion
Jun 2007
Last update
Sep 14, 2007

Study contacts

Marie-Pierre St-Onge, Ph.D
principal investigator · St. Luke's-Roosevelt Hospital Center

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2007. You cannot join it, but the record below documents what was studied.

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