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CompletedNCT00520858Updated Apr 22, 2008

Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

An interventional study of Resistance Exercise (RE) and Aerobic Exercise (AE) in Abdominal Obesity, sponsored by Queen's University. Completed at 1 site in Canada. Open to participants aged 65 Years to 80 Years. Per ClinicalTrials.gov, last updated 2008-04-22.

Sponsored by Queen's University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
145
Ages
65 Years to 80 Years
Sex
All
01

Study summary

The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires an innovative approach. We propose a novel approach to investigate the effects of different exercise types as independent treatment strategies for the reduction of obesity and related health risk factors in older men and women. We propose that exercise without caloric restriction will be associated with modest weight loss (3-5%), that in turn will be associated with significant reduction in abdominal obesity, insulin resistance, and a corresponding increase in skeletal muscle mass and function. We will determine the separate effects of resistance and aerobic exercise on these primary outcome variables, and, whether a treatment strategy that combines the two is optimal.

02

Conditions studied

  • Abdominal Obesity
03

In context

Obesity

6,296 studies on the registry are indexed under Obesity; 1,692 are open to participants now.

This study's enrollment of 145 is above the median of 78 across 4,878 interventional studies indexed under Obesity.

Browse Obesity studies →

Lead sponsor

Queen's University is the lead sponsor of 199 studies on the registry; 16 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years to 80 Years
Sexes eligible
All

Inclusion criteria

  • Men and women between 65 and 80 years of age.
  • Men and women are self-sufficient, sedentary, abdominally obese (BMI between 27 and 34.9 kg/m2; waist circumference greater than 88 cm in women and 102 cm in men), weight stable (± 2 kg) for 6 months prior to the beginning of the study, be non-smokers, and not diabetic.
  • We will study elderly women who are not taking hormone replacement therapy to create a homogeneous population in whom the effect of exercise on the principal outcome variables can be evaluated with minimal confounding.

Exclusion criteria

Exclusion Criteria:

  • Smokers and diabetics.
  • Women taking hormone replacement therapy.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
145 participants (actual)

Study arms

  • No intervention
    C
  • Active comparator
    RE

    Resistance Exercise

    Other: Resistance Exercise (RE)

  • Active comparator
    AE

    Aerobic Exercise

    Other: Aerobic Exercise (AE)

  • Active comparator
    RAE

    Resistance and Aerobic

    Other: Resistance and Aerobic Exercise (RAE)

Interventions

  • OtherResistance Exercise (RE)
  • OtherAerobic Exercise (AE)
  • OtherResistance and Aerobic Exercise (RAE)
06

What researchers measure

Primary outcomes

  1. Abdominal obesity

    Time frame: 6 months

Secondary outcomes

  1. Insulin Resistance

    Time frame: 6 Months

07

Study locations

1 site
  • Queen's University
    Kingston, Ontario K7L 3N6, Canada
08

References and documents

Publications

  • Davidson LE, Hudson R, Kilpatrick K, Kuk JL, McMillan K, Janiszewski PM, Lee S, Lam M, Ross R. Effects of exercise modality on insulin resistance and functional limitation in older adults: a randomized controlled trial. Arch Intern Med. 2009 Jan 26;169(2):122-31. doi: 10.1001/archinternmed.2008.558. PubMed 19171808 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 22, 2008, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00520858
Lead sponsor
Queen's University
Collaborators
Canadian Institutes of Health Research (CIHR)
First posted
Aug 27, 2007
Start date
Sep 2003
Last update
Apr 22, 2008

Study contacts

Robert Ross
principal investigator · Queen's University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2008. You cannot join it, but the record below documents what was studied.

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