An interventional study of misoprostol and surgery in Incomplete Abortion, sponsored by Gynuity Health Projects. Completed at 6 sites in 5 countries. Open to female participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-03-30.
Sponsored by Gynuity Health Projects · Not applicable, Interventional, and Treatment
In this study, we will compare the safety and efficacy of 400 mcg sublingually administered misoprostol alone to standard surgical care for the treatment of incomplete abortion. This study will provide important data on the role of misoprostol in health services offering an array of treatments for incomplete abortion. Women could significantly benefit from a non-invasive treatment option for incomplete abortion. While safe surgical services are becoming more widespread, there is still a serious risk of complications from these procedures. Especially in developing countries, infection, hemorrhage and uterine damage are still too common. Medical treatment of incomplete abortion using misoprostol would be a tremendous step to reducing morbidity and mortality due to abortion complications.
24 studies on the registry are indexed under Abortion, Incomplete; 5 are open to participants now.
This study's enrollment of 1,000 is above the median of 311 across 21 interventional studies indexed under Abortion, Incomplete.
Browse Abortion, Incomplete studies →Gynuity Health Projects is the lead sponsor of 113 studies on the registry; 2 are open to participants now.
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Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
standard surgical treatment (either dilation and curettage or manual vacuum aspiration)
Procedure: surgery
400 mcg misoprostol
Drug: misoprostol
single dose of 400 mcg misoprostol administered sublingually
standard surgical treatment (dilation and curettage or manual vacuum aspiration)
Complete abortion without recourse to surgical intervention.
Time frame: follow up visit 7 days after initial treatment
This study is completed, as verified in Mar 2012. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Misoprostol