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CompletedNCT00463255Updated Nov 8, 2011

Diet and the Aging Brain

A Phase 3 interventional study of diet in Healthy, sponsored by University Hospital Muenster. Completed at 1 site in Germany. Open to participants aged 50 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-11-08.

Sponsored by University Hospital Muenster · Phase 3, Interventional, and Prevention

Phase
Phase 3
Study type
Interventional
Enrollment
120
Allocation
Randomized
Ages
50 Years to 80 Years
Sex
All
01

Study summary

We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.

Read the detailed description

The age-related degradation of cognitive functions even to the point of neurodegenerative disorders such as alzheimer's disease are a growing public-health concern with potentially devastating effects.

Refering to animal data and empirical studies, a healthy diet rich in unsaturated fatty acids and low in calories should improve cognitive functions such as learning and memory. To test this hypothesis, we study general brain functions in healthy elderly subjects (50-80 years old) during a short term diet.

02

Conditions studied

  • Healthy

Keywords

  • Diet
  • elderly
  • age-related diseases
  • prevention
  • cognitive decline
  • Clinical study
03

In context

Lead sponsor

University Hospital Muenster is the lead sponsor of 189 studies on the registry; 18 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • healthy subjects
  • 50-80 years old
  • moderate to heavy weight
  • must be able to change diet at home

Exclusion criteria

Exclusion Criteria:

  • diabetes
  • younger than 50 years
  • BMI \< 23
  • already participating in other studys
  • MMSE > 26
  • eating disorders
05

Study design

Phase
Phase 3
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
120 participants (estimated)

Interventions

  • Behavioraldiet
06

What researchers measure

Primary outcomes

  1. implicit visual-motor learning of a finger sequence of the hand.

Secondary outcomes

  1. implicit learning of an artificial language

  2. several plasma levels related to cognitive functions

07

Study locations

1 site
  • University Hospital Muenster, Department of Neurology
    Muenster, NRW 48149, Germany
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 8, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00463255
Lead sponsor
University Hospital Muenster
First posted
Apr 20, 2007
Start date
Aug 2006
Completion
Oct 2008
Last update
Nov 8, 2011

Study contacts

Stefan Knecht, MD, Prof.
study chair · University Hospital Muenster
Bernd E Ringelstein, MD, Prof
study chair · University Hopsital Muenster
Agnes Floeel, MD
principal investigator · University Hospital Muenster

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2011. You cannot join it, but the record below documents what was studied.

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