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Status unknownNCT00451737Updated Mar 23, 2007

Correlation of 6-Minute Walk Test and Neuromuscular Parameters in the Elderly

A Phase 1 interventional study of Isokinetic test in Healthy, sponsored by National Taiwan University Hospital. Status unknown at 1 site in Taiwan. Open to participants aged 65 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2007-03-23.

Sponsored by National Taiwan University Hospital · Phase 1, Interventional, and Diagnostic

The sponsor has not verified this record recently (last verified Jan 2006), so the status shown — last known as Recruiting — may be out of date.
Phase
Phase 1
Study type
Interventional
Enrollment
100
Allocation
Randomized
Ages
65 Years to 85 Years
Sex
All
01

Study summary

The six-minute walk test had been used to assessment the cardiopulmonary parameter in patients with lung and heart disease. And it has good reliability and validity. It has been used extensively in research into the aerobic capacity in patients of peripheral vascular disease, neural system disease, and even the muscular-skeletal system disease, such as osteoarthritis, total hip or knee arthroplasty. There were studies investigate the predictors based on cardiopulmonary factors, neuromuscular and skeletal factors of the six-minute walk distance. But the last is the neuromuscular and skeletal factors.

The purpose of this study is to investigate the correlations between the six-minute walk distance and neuromuscular parameters: muscle function (including muscle endurance, muscle strength and muscle power), knee proprioception, and standing balance. For that it could be more useful for evaluation and treatment patients in clinic.

The study was planed to select 100 subjects, they are older than 65 years old with independent walking and without any diagnosis or symptoms about cardiopulmonary or neural disease. The evaluation are including knee proprioception (closed chain, active-active test), six-minute walk test, one leg standing balance test (open and close eyes for 30 seconds), quadriceps muscle strength at velocities of 600/s,1200/s and 1800/s, quadriceps muscle power at 1800/s, and quadriceps muscle endurance.

To investigate the correlations between the six-minute walk distance and characteristics of subjects, the correlations between six-minute walk distance and neuromuscular parameters, including quadriceps muscle function (strength, endurance and power), knee proprioception, and one leg standing balance. And to analyze what's the most contribution to the six-minute walk distance.

02

Conditions studied

  • Healthy

Keywords

  • Six-minute walk test
  • Neuromuscular system
  • Influence factors
03

In context

Lead sponsor

National Taiwan University Hospital is the lead sponsor of 2,609 studies on the registry; 574 are open to participants now.

Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • older than 65 years old
  • independent walking

Exclusion criteria

Exclusion Criteria:

  • diagnosis or symptoms about cardiopulmonary or neural disease
  • depression
05

Study design

Phase
Phase 1
Primary purpose
Diagnostic
Allocation
Randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
100 participants

Interventions

  • DeviceIsokinetic test
06

What researchers measure

Primary outcomes

  1. six-minute walking test

  2. knee joint reposition test

  3. knee joint muscle strength

  4. ankle joint muscle strength

  5. knee joint muscle endurance

  6. one leg standing balance

07

Study locations

1 of 1 sites recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 23, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00451737
First posted
Mar 23, 2007
Start date
Nov 2006
Completion
Mar 2007 (estimated)
Last update
Mar 23, 2007

Study contacts

Jan Mei Hwa, MS
study director · kinesiology laborary of physical therapy in NTU
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2006. You cannot join it, but the record below documents what was studied.

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