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CompletedNCT00339872Updated Dec 5, 2007

Study Evaluating IMA-638 in Asthma

A Phase 1 interventional study of IMA-638 in Asthma, sponsored by Wyeth is now a wholly owned subsidiary of Pfizer. Completed at 1 site in United States. Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2007-12-05.

Sponsored by Wyeth is now a wholly owned subsidiary of Pfizer · Phase 1, Interventional, and Diagnostic

Phase
Phase 1
Study type
Interventional
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
All
01

Study summary

The purpose of this study is to evaluate the safety of, and blood drug levels for, single, ascending doses of IMA-638 in mild to moderate asthma subjects.

02

Conditions studied

  • Asthma

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Keywords

  • healthy subjects
03

In context

Asthma

3,921 studies on the registry are indexed under Asthma; 507 are open to participants now.

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Lead sponsor

Wyeth is now a wholly owned subsidiary of Pfizer is the lead sponsor of 472 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No

Eligibility criteria

Inclusion Criteria:

  • Men and women of non-childbearing potential with mild to moderate asthma as defined by forced expiratory volume in 1 second (FEV1) greater than 70% predicted.
  • Well controlled asthma, as exhibited by completion of asthma questionnaire.
  • Otherwise healthy, except for asthma.
05

Study design

Phase
Phase 1
Primary purpose
Diagnostic
Allocation
Randomized
Intervention model
Single group
Masking
Double

Interventions

  • DrugIMA-638
06

What researchers measure

Primary outcomes

  1. Safety will be measured by evaluating physical examinations, spirometry, vital signs, electrocardiograms (ECGs), and clinical laboratory test results.

Secondary outcomes

  1. Drug levels in the blood and associated biomarkers will be evaluated.

07

Study locations

1 site
  • Denver, Colorado 80230, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 5, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00339872
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
First posted
Jun 21, 2006
Start date
Feb 2006
Completion
Apr 2007
Last update
Dec 5, 2007

Study contacts

Medical Monitor
study director · Wyeth is now a wholly owned subsidiary of Pfizer
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2007. You cannot join it, but the record below documents what was studied.

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