An observational study in Heart Failure and Myocardial Infarct, sponsored by Helse Stavanger HF. Completed at 1 site in Norway. Per ClinicalTrials.gov, last updated 2015-07-28.
Sponsored by Helse Stavanger HF · Observational
This study will assess the relationship between collagen turnover, neurohormonal activation, scarring and left ventricle remodelling in patients 3 years following a myocardial infarction.
A multinational trial compared losartan vs. captopril in 5477 postinfarction patients with symptoms of heart failure and/or evidence of left ventricular dysfunction. The trial was terminated in 2002 and the results of the main trial have been published. In this trial, a collagen and neurohumoral substudy was performed to assess the importance of collagen turnover in this population. A total of 235 patients were included from 18 centres. Blood was taken at randomisation, 1 month, 1 year and 2 years.
The present study will recruit surviving patients among the 119 individuals that were randomised to the neurohumoral substudy at the Stavanger University Hospital. The study will assess the relationship between collagen turnover, neurohormonal activation, scarring and left ventricle remodelling in these patients about 3 years following the index myocardial infarction.
The data collected at the 3-year follow-up visit will be compared to data from the initial study.
2,744 studies on the registry are indexed under Myocardial Infarction; 418 are open to participants now.
This study's enrollment of 119 is below the median of 500 across 983 observational studies indexed under Myocardial Infarction.
Browse Myocardial Infarction studies →Helse Stavanger HF is the lead sponsor of 93 studies on the registry; 17 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with risk of heart failure secondary to myocardial infarct.
Exclusion Criteria:
This study is completed, as verified in Jul 2010. You cannot join it, but the record below documents what was studied.
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Helse Stavanger HF