An observational study in Respiratory Failure and Botulism, sponsored by Rajavithi Hospital. Completed at 1 site in Thailand. Open to participants aged 1 Year and older. Per ClinicalTrials.gov, last updated 2008-10-24.
Sponsored by Rajavithi Hospital · Observational
Background. Northern Thailand's biggest botulism outbreak to date occurred on 14 March 2006 and affected 209 people. Of these, 42 developed respiratory failure, and 25 of those who developed respiratory failure were referred to 9 high facility hospitals for treatment of severe respiratory failure and autonomic nervous system involvement. Among these patients, we aimed to assess the relationship between the rate of ventilator dependence and the occurrence of treatment by day 4 versus day 6 after exposure to bamboo shoots (the source of the botulism outbreak), as well as the relationship between ventilator dependence and negative inspiratory pressure.
Methods. The investigators reviewed the circumstances and timing of symptoms following exposure. Mobile teams treated patients with botulinum antitoxin on day 4 or day 6 after exposure in Nan Hospital (Nan, Thailand). Eighteen patients (in 7 high facility hospitals) with severe respiratory failure received a low- and high-rate repetitive nerve stimulation test, and negative inspiratory pressure was measured.
1,369 studies on the registry are indexed under Respiratory Insufficiency; 264 are open to participants now.
This study's enrollment of 18 is below the median of 100 across 455 observational studies indexed under Respiratory Insufficiency.
Browse Respiratory Insufficiency studies →Rajavithi Hospital is the lead sponsor of 46 studies on the registry; none are open to participants now.
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The record gives a start of Mar 2006 and a completion of Apr 2006. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Aug 2007. You cannot join it, but the record below documents what was studied.
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Rajavithi Hospital