A Phase 2 interventional study of Exercise training and Exercise training in Coronary Artery Bypass, sponsored by Norwegian University of Science and Technology. Terminated at 1 site in Norway. Per ClinicalTrials.gov, last updated 2010-05-18.
Sponsored by Norwegian University of Science and Technology · Phase 2, Interventional, and Treatment
The purpose of this study is to investigate the effect of high and moderate intensity exercise training after coronary bypass surgery. The subjects are randomised to training at either 60-70% or 85-95% of their maximal capacity daily for four weeks. Primary outcome measure is change in maximal aerobic capacity, measured as change in maximal oxygen consumption, after the training period. Secondary outcome measures are change in quality of life, heart rate variability, ultrasound measures of the heart and blood variables, including endothelian markers.
The exercise part of cardiac rehabilitation today is often composed of low to moderate intensity training. Several studies have found interval training with high intensity to be more effective in improving physical capacity in healthy subjects and also in different patient populations. We therefore wish to compare high intensity interval training with moderate intensity training in patients operated with coronary bypass surgery. Maximal oxygen consumption is shown to be the best indicator of how many years you life, both in healthy persons and in cardiac patients.
The subjects in this study is attending a four week rehabilitation program at an residential institution in Norway. They are randomised to do either a moderate or a high intensity aerobic training session each day.
The hypothesis in advance, was that high intensity interval training lead to a greater improvement in maximal oxygen consumption than training with moderate intensity. We also hypothesised that there would be no difference between the two groups after 6 months, since then the patients had to administer their own exercise training.
Norwegian University of Science and Technology is the lead sponsor of 487 studies on the registry; 52 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Interval exercise training with high intensity
Behavioral: Exercise training
Exercise training with moderate intensity
Behavioral: Exercise training
Interval exercise training with high intensity five days per week for four weeks.
Exercise training with moderate intensity, five days per week for four weeks.
Oxygen Consumption
Quality of life
Pulse
Blodverdier
Ekkokardiografiske parametre
This study is terminated, as verified in Apr 2008. You cannot join it, but the record below documents what was studied.
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Norwegian University of Science and Technology