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CompletedNCT00225459Updated Oct 5, 2011

Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.

An observational study in Anxiety Disorder and Mood Disorder, sponsored by University of Saskatchewan. Completed at 1 site in Canada. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2011-10-05.

Sponsored by University of Saskatchewan · Observational

Study type
Observational
Model
Case-crossover
Time perspective
Prospective
Enrollment
200
Ages
18 Years to 70 Years
Sex
All
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Study summary

The purpose of this study is to determine whether or not spiritual and/or religious commitment affects mood variability and thoughts of suicide.

First we hypothesize that among patients with depressive symptoms, those who have higher religious/spiritual (R/S) commitment will have less suicidal ideation and less mood variability. Second, we hypothesize that higher mood variability will be associated with more suicidal ideation. Finally, dependent on the first two hypotheses, we propose that R/S commitment will mediate the relationship between mood variability and suicidal ideation.

Read the detailed description

The suicide rate has not changed dramatically in the recent past, despite advances in psychiatric and mental health treatment, suicide prevention and awareness programs, and reorganization of health services. Depression and the mood disorders which may affect 15% of the population are the conditions most associated with high suicide rates (in addition to psychotic conditions that are relatively rare). Research findings into specific conditions within the depressive disorders that might predict suicidal tendencies are sparse, except for other common comorbid conditions such as panic and alcohol abuse. Research into risks and protective factors has infrequently included religious and spiritual variables that have been associated with decreased rates of depression, suicide, suicide attempts and suicidal ideation.

An inverse relationship between religion and suicide has been found in regional, national, and cross-national studies. Analyzing data from the 1993 Mortality Followback Survey in the US, frequency of religious activities reduced the odds of dying by suicide even after controlling for the frequency of social contact; in 584 deaths by suicide compared with 4279 natural deaths. A Canadian study of 261 Census divisions found the absence of religious affiliation to be an important predictor of death by suicide.

There are no known studies examining mood variability and religion, or spirituality directly. A number of studies however have examined personality attributes and religiosity. The personality style of neuroticism includes moodiness and negative emotionality with the concept of mood reactivity being germane to its construct. Neuroticism is highly correlated with depression and may be a higher order factor in the "internalizing disorders" which include the depressive and anxiety disorders.

The objective of this study is to answer the question "Does R/S mediate the relationship between mood variability and suicidal ideation?" In an effort to achieve that objective, there are three questions that must be answered in this population which in themselves are significant contributions to the research literature.

  1. Is there an association between mood variability and suicidal ideation?
  2. Is there an association between mood variability and religion?
  3. Is there an association between religion and suicidal ideation?

We hypothesize that those who endorses higher religious/spiritual commitment as measured by daily spiritual experiences, positive religious coping, and personal devotion, will have less suicidal ideation, and less mood variability. Secondly, we hypothesize that higher mood variability will be associated with more suicidal ideation. Finally, dependent on the first two hypotheses, we propose that R/S commitment will mediate the relationship between mood variability and suicidal ideation.

02

Conditions studied

  • Anxiety Disorder
  • Mood Disorder

Keywords

  • Religious psychology
  • Anxiety disorder
  • Mood disorder
  • Suicide
03

In context

Anxiety Disorders

4,868 studies on the registry are indexed under Anxiety Disorders; 1,390 are open to participants now.

This study's planned enrollment of 200 is above the median of 150 across 606 observational studies indexed under Anxiety Disorders.

Browse Anxiety Disorders studies →

Lead sponsor

University of Saskatchewan is the lead sponsor of 237 studies on the registry; 33 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study population is psychiatric inpatients and outpatients with depressive symptoms between the ages or 18 and 70. Co-morbid anxiety, bipolar spectrum, and eating disorders will be allowed. Involuntary patients and those with psychosis, organic brain impairment, and current substance dependence will be excluded. We will recruit patients prospectively, as they attend psychiatrists' clinics and are admitted to hospital.

Inclusion criteria

  • Inpatients and outpatients.
  • DSM-IV defined major depression.
  • Comorbid anxiety, bipolar spectrum, and schizoaffective (depressive type).
  • Males and females between the ages of 18 and 70.

Exclusion criteria

Exclusion Criteria:

  • Involuntary patients.
  • In/out patients with current psychosis.
  • In/out patients with neurological impairment.
  • In/out patients with current substance dependence.
05

Study design

Observational model
Case-crossover
Time perspective
Prospective
Enrollment
200 participants (estimated)
06

Study locations

1 site
  • University of Saskatchewan Department of Psychiatry
    Saskatoon, Saskatchewan S7N 0W8, Canada
07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 5, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00225459
Lead sponsor
University of Saskatchewan
Collaborators
Saskatoon Health Region
Responsible party
Marilyn Baetz (Professor of Psychiatry, University of Saskatchewan) — Principal investigator
First posted
Sep 23, 2005
Start date
Jun 2005
Completion
Dec 2008
Last update
Oct 5, 2011

Study contacts

Marilyn Baetz, MD
principal investigator · University of Saskatchewan
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2011. You cannot join it, but the record below documents what was studied.

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