An observational study in Tinea Capitis, sponsored by Children's Mercy Hospital Kansas City. Completed at 1 site in United States. Open to participants aged 2 Years to 5 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-09-19.
Sponsored by Children's Mercy Hospital Kansas City · Observational
To explore carrier and infection status of T.tonsurans tinea capitis and characterize the host-pathogen interaction as it relates to the disease presentation. The general hypothesis for this study is as follows: the type of genotypic and phenotypic variant to which a child is exposed accounts for the presentation status observed in Trichophyton tonsurans infection.The global outcome of this investigation is to reveal potential new drug targets designed to improve treatment outcomes in these children.
Tinea capitis is an overwhelmingly prevalent disease of childhood estimated to be present in approximately 1 in 20 children at any point in time with an equal number of children serving as carriers of the fungal pathogen. Despite the widespread nature of the disease, the natural course of the infection remains incompletely described. The study will be driven by the following hypothesis: the type of genotypic and phenotypic variant to which a child is exposed accounts for the presentation status observed in Trichophyton tonsurans infection.
A fungal scalp culture will be acquired from all participants using a brush culture technique. Samples will be collected once a month over a two year time period.
Children's Mercy Hospital Kansas City is the lead sponsor of 209 studies on the registry; 22 are open to participants now.
Of its 18 completed or terminated interventional studies of FDA-regulated products, 14 (78%) have results posted.
Counted across the registry records on this site, refreshed daily.
preschool aged children
Exclusion Criteria:
sterile, soft-head toothbrush massaged on scalp
This study is completed, as verified in Sep 2011. You cannot join it, but the record below documents what was studied.
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Tinea Capitis
Children's Mercy Hospital Kansas City