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CompletedNCT00222092Updated Aug 24, 2011

Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers

An observational study in Post-ERCP Acute Pancreatitis, sponsored by University of Ioannina. Completed at 1 site in Greece. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-08-24.

Sponsored by University of Ioannina · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
300
Ages
18 Years and older
Sex
All
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Study summary

Octreotide, somatostatin and pentoxyfilline commercially available drugs that are used in various clinical situations. They are safe and known for years. Octreotide and somatostatin have been used in many studies for the prophylaxis and treatment of pancreatitis and post-ERCP pancreatitis, while pentoxyfilline has shown effect on patients with alcoholic hepatitis, obstructive vasculitis etc. The aim of the study is to evaluate the efficacy of any of those treatments for the prophylaxis and treatment of post-ERCP pancreatitis. In addition some molecular markers of acute and chronic inflammation will be measured before and after the endoscopic procedures according to the study protocol.

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Conditions studied

  • Post-ERCP Acute Pancreatitis

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Keywords

  • post-ERCP pancreatitis
  • prophylaxis
  • prognosis
  • natural course
  • molecular markers
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In context

Pancreatitis

752 studies on the registry are indexed under Pancreatitis; 181 are open to participants now.

This study's enrollment of 300 is above the median of 180 across 277 observational studies indexed under Pancreatitis.

Browse Pancreatitis studies →

Lead sponsor

University of Ioannina is the lead sponsor of 53 studies on the registry; 14 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

patients undergoing endoscopic retrograde cholangiopancreatography

Inclusion criteria

  • patients undergoing endoscopic retrograde cholangiopancreatography

Exclusion criteria

Exclusion Criteria:

  • children, pregnant or breastfeeding women
  • patients with coagulation disorders
  • inability to access the papilla of Vater due to technical difficulties (previous surgery, malignant obstruction)
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
300 participants
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Study locations

1 site
  • Hepato-Gastroenterology Unit, Medical School of Ioannina - Greece
    Ioannina, 45110, Greece
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 24, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00222092
Lead sponsor
University of Ioannina
First posted
Sep 22, 2005
Start date
Sep 2005
Completion
Sep 2006
Last update
Aug 24, 2011

Study contacts

Dimitrios Sigounas, MD
principal investigator · University of Ioannina
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2005. You cannot join it, but the record below documents what was studied.

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