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CompletedNCT00213850Updated Dec 22, 2025

Reference Values for Respiratory Resistance Measured by the Interrupter Technique in Adults

An interventional study of EFR in Healthy, sponsored by University Hospital, Strasbourg, France. Completed at 1 site in France. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-22.

Sponsored by University Hospital, Strasbourg, France · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
122
Allocation
Non-randomized
Ages
18 Years and older
Sex
All
01

Study summary

The purpose is to obtain reference values of respiratory resistance (a technique widely used in children), in adults. The interest is that this technique needs only little co-operation and would be particularly adapted in subjects in whom co-operation is insufficient for other measurements.

02

Conditions studied

  • Healthy

Keywords

  • Interrupter technique
  • Respiratory resistance
  • Normal adults
03

In context

Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 966 studies on the registry; 342 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Inclusion Criteria:

  • Adult non smokers, without any disease interfering with pulmonary function
05

Study design

Phase
Not applicable
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
122 participants (actual)

Interventions

  • ProcedureEFR
06

What researchers measure

Primary outcomes

  1. References values obtained once

Secondary outcomes

  1. Estimation of short-term reproductibility

07

Study locations

1 site
  • Service de Physiologie Clinique et des Explorations Fonctionnelles, Hôpital Civil
    Strasbourg, 67091, France
08

References and documents

Publications

  • Oswald-Mammosser M, Charloux A, Enache I, Lonsdorfer-Wolf E. The opening interrupter technique for respiratory resistance measurements in children. Respirology. 2010 Oct;15(7):1104-10. doi: 10.1111/j.1440-1843.2010.01828.x. PubMed 20874747 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 22, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00213850
Lead sponsor
University Hospital, Strasbourg, France
Responsible party
Sponsor
First posted
Sep 21, 2005
Start date
Jan 2002
Completion
Sep 2006
Last update
Dec 22, 2025

Study contacts

Monique OSWALD-MAMMOSSER, MD
principal investigator · Service de Physiologie Clinique et des Explorations Fonctionnelles, Hôpitaux Universitaires de Strasbourg
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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