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CompletedNCT00199329Updated Mar 21, 2018

Antiemetic Effect of the Addition of Ondansetron to the Morphine Solution in Patient-Controlled Analgesia (PCA)

An interventional study of ondansetron adding in PCA in Postoperative Nausea and Vomiting, sponsored by Khon Kaen University. Completed at 1 site in Thailand. Open to participants aged 15 Years to 60 Years. Per ClinicalTrials.gov, last updated 2018-03-21.

Sponsored by Khon Kaen University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
160
Allocation
Randomized
Ages
15 Years to 60 Years
Sex
All
01

Study summary

PCA morphine always introduces nausea and vomiting during the postoperative period. Ondansetron can reduce PONV (postoperative nausea vomiting). We, the researchers at Khon Kaen University, are trying to add ondansetron in PCA morphine. Patients receive a small dose of ondansetron when they request morphine.

02

Conditions studied

  • Postoperative Nausea and Vomiting

Keywords

  • ondansetron
  • PCA
03

In context

Vomiting

1,100 studies on the registry are indexed under Vomiting; 134 are open to participants now.

This study's enrollment of 160 is above the median of 107 across 935 interventional studies indexed under Vomiting.

Browse Vomiting studies →

Lead sponsor

Khon Kaen University is the lead sponsor of 160 studies on the registry; 24 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age between 15-60 years old

Exclusion criteria

Exclusion Criteria:

  • History of motion sickness, smoking
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
160 participants (actual)

Interventions

  • Drugondansetron adding in PCA
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What researchers measure

Primary outcomes

  1. PONV

    Time frame: 24 hr

07

Study locations

1 site
  • Khon Kaen university, Srinagarind Hospital
    Muang, Khon Kaen 40002, Thailand
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 21, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00199329
Lead sponsor
Khon Kaen University
First posted
Sep 20, 2005
Start date
Jan 2005
Last update
Mar 21, 2018

Study contacts

Polpun Boonmak, MD
study director · lecturer in Khon Kaen University
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2007. You cannot join it, but the record below documents what was studied.

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