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CompletedNCT00180817Updated Aug 8, 2022

Longitudinal Study of the Clinical and Haematological Cause of Women With Antiphospholipid Antibodies.

An observational study in Antiphospholipid Syndrome, sponsored by Imperial College London. Completed at 1 site in United Kingdom. Open to female participants. Per ClinicalTrials.gov, last updated 2022-08-08.

Sponsored by Imperial College London · Observational

Study type
Observational
Time perspective
Other
Enrollment
250
Sex
Female
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Study summary

This study is being done to see if there are any long term health related issues in women with APA and recurrent miscarriages.

Read the detailed description

The association between APA and thrombosis is well documented. Both LA and ACA are often detected in individuals with SLE but there is no prospective data on the risk of thrombosis in women who present with recurrent miscarriages in association with APA. This study should significantly advance medical knowledge of the natural history of primary antiphospholipid syndrome (PAPS) which is essential to enable optimal management of relatively young women who may be at risk of complications, some of which are potentially life threatening.

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Conditions studied

  • Antiphospholipid Syndrome

Keywords

  • Antiphospholipid syndrome
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In context

Antiphospholipid Syndrome

121 studies on the registry are indexed under Antiphospholipid Syndrome; 51 are open to participants now.

This study's planned enrollment of 250 is above the median of 181 across 52 observational studies indexed under Antiphospholipid Syndrome.

Browse Antiphospholipid Syndrome studies →

Lead sponsor

Imperial College London is the lead sponsor of 824 studies on the registry; 178 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 6 (67%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

Antiphospholipid syndrome History of recurrent miscarriages

Exclusion criteria

Exclusion Criteria:

Previous thromboembolic disease

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Study design

Time perspective
Other
Enrollment
250 participants (estimated)
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Study locations

1 site
  • St. Mary's Hospital
    London, W2 1NY, United Kingdom
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 8, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00180817
Lead sponsor
Imperial College London
Responsible party
Sponsor
First posted
Sep 16, 2005
Start date
Sep 1998
Primary completion
Aug 31, 2005
Completion
Aug 31, 2005
Last update
Aug 8, 2022

Study contacts

Lesley Regan
principal investigator · Imperial College London
Raj Rai, MRCOG
principal investigator · Imperial College London
Winnie Lo
principal investigator · St. Mary's NHS Trust, London
Preeti Jindal, MRCOG
principal investigator · St. Mary's NHS Trust, London
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.

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