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CompletedNCT00111891Updated Feb 17, 2017

An Investigational Drug Study Evaluating a Novel Approach to Treat Dyslipidemia (0524A-032)

A Phase 2 interventional study of niacin (+) laropiprant and Comparator: placebo (unspecified) in Dyslipidemia, sponsored by Merck Sharp & Dohme LLC. Completed. Open to participants aged 25 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-02-17.

Sponsored by Merck Sharp & Dohme LLC · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Enrollment
575
Allocation
Randomized
Ages
25 Years to 75 Years
Sex
All
01

Study summary

This is a 3-week trial in normal healthy or lipid clinic patients studying a novel approach to treating dyslipidemia.

Read the detailed description

The duration of treatment is 7 days.

02

Conditions studied

  • Dyslipidemia

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03

In context

Dyslipidemias

1,073 studies on the registry are indexed under Dyslipidemias; 158 are open to participants now.

This study's enrollment of 575 is above the median of 99 across 842 interventional studies indexed under Dyslipidemias.

Browse Dyslipidemias studies →

Lead sponsor

Merck Sharp & Dohme LLC is the lead sponsor of 2,114 studies on the registry; 133 are open to participants now.

Of its 489 completed or terminated interventional studies of FDA-regulated products, 362 (74%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
25 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Males and females (ages 25-75)

Exclusion criteria

Exclusion Criteria:

  • A condition which, in the opinion of the investigator, might pose a risk to the patient or interfere with participating in the study
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
575 participants (actual)

Interventions

  • Drugniacin (+) laropiprant

    Also known as: MK0524A

  • DrugComparator: placebo (unspecified)
06

What researchers measure

Primary outcomes

  1. Acute cutaneous symptoms induced by niacin for 7 days.

    Time frame: 7 days

Secondary outcomes

  1. Tolerability

    Time frame: 7 days

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 17, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00111891
Lead sponsor
Merck Sharp & Dohme LLC
Responsible party
Sponsor
First posted
May 27, 2005
Start date
Jun 2005
Primary completion
Aug 2005
Completion
Aug 2005
Last update
Feb 17, 2017

Study contacts

Medical Monitor
study director · Merck Sharp & Dohme LLC
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2017. You cannot join it, but the record below documents what was studied.

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