A Phase 1 interventional study of conventional surgery and radiofrequency ablation in Head and Neck Cancer, sponsored by University of California, San Francisco. Status unknown at 1 site in United States. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2013-09-20.
Sponsored by University of California, San Francisco · Phase 1, Interventional, and Treatment
RATIONALE: Radiofrequency ablation uses a high-frequency, electric current to kill tumor cells. Ultrasound-guided radiofrequency ablation may be effective treatment for thyroid cancer.
PURPOSE: This phase I trial is studying the side effects of radiofrequency ablation in treating patients who are undergoing surgery for thyroid cancer.
OBJECTIVES:
OUTLINE: This is a pilot study.
An electrosurgical probe is placed by ultrasound guidance into the center of the thyroid tumor. Patients undergo radiofrequency ablation directly to the tumor until the target temperature is reached* for 5 minutes. Patients then undergo standard thyroidectomy.
NOTE: *Takes approximately 15-30 minutes to reach target temperature.
After completion of study treatment, patients are followed at day 1, between days 14-21, and then periodically as deemed necessary.
PROJECTED ACCRUAL: A total of 15-40 patients will be accrued for this study.
802 studies on the registry are indexed under Thyroid Neoplasms; 216 are open to participants now.
Browse Thyroid Neoplasms studies →University of California, San Francisco is the lead sponsor of 2,132 studies on the registry; 375 are open to participants now.
Of its 262 completed or terminated interventional studies of FDA-regulated products, 196 (75%) have results posted.
Counted across the registry records on this site, refreshed daily.
DISEASE CHARACTERISTICS:
Cytologically confirmed papillary thyroid cancer by fine needle aspiration
Intrathyroidal tumor
PATIENT CHARACTERISTICS:
Age
Performance status
Life expectancy
Hematopoietic
Hepatic
Renal
PRIOR CONCURRENT THERAPY:
Biologic therapy
Chemotherapy
Endocrine therapy
Radiotherapy
Surgery
Frequency of radiofrequency ablation-associated complications at 2 weeks
Amount of tumor destruction at 2 weeks
This study is status unknown, as verified in Aug 2005. You cannot join it, but the record below documents what was studied.
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University of California, San Francisco