CClinicalTrials.gg
CompletedNCT00096928RESPONSEUpdated Jul 2, 2015

A Study to Evaluate Psoriasis Outcomes and Safety Events in Patients With Chronic Moderate to Severe Plaque Psoriasis (RESPONSE)

An observational study in Psoriasis, sponsored by Genentech, Inc.. Completed at 182 sites in United States. Per ClinicalTrials.gov, last updated 2015-07-02.

Sponsored by Genentech, Inc. · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
1,846
Sex
All
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Study summary

This was a multicenter, prospective, 5-year surveillance study of approximately 5000 Raptiva-treated patients and approximately 500 non-Raptiva treated patients (formerly 2500 comparison patients who were treated with a biologic therapy other than Raptiva) with chronic moderate to severe plaque psoriasis who were candidates for treatment with Raptiva.

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Conditions studied

  • Psoriasis

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Keywords

  • Plaque Psoriasis
  • RESPONSE
  • Raptiva
  • efalizumab
03

In context

Psoriasis

1,899 studies on the registry are indexed under Psoriasis; 233 are open to participants now.

This study's enrollment of 1,846 is above the median of 200 across 396 observational studies indexed under Psoriasis.

Browse Psoriasis studies →

Lead sponsor

Genentech, Inc. is the lead sponsor of 507 studies on the registry; 23 are open to participants now.

Of its 90 completed or terminated interventional studies of FDA-regulated products, 50 (56%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

managed care organizations, community or physician practices, and academic centers in the United States

Inclusion criteria

  • Have ever had a physician's diagnosis of chronic moderate to severe plaque psoriasis and be a candidate for treatment with Raptiva
  • Are being treated with or initiating Raptiva therapy at the time of enrollment
  • Be able to provide written informed consent
  • Be willing and able to fully to participate for the duration of patient follow-up (5 years)

Exclusion criteria

Exclusion Criterion:

  • Have previously received at least one dose of Raptiva and are not currently using or restarting treatment with Raptiva at the time of enrollment
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
1,846 participants (actual)
06

Study locations

182 sites
  • Total Skin and Beauty Dermatology Center
    Birmingham, Alabama 35205, United States
  • Deep South Dermatology
    Daphne, Alabama 36526, United States
  • The Dermatology Center
    Gadsden, Alabama 35901, United States
  • Medical Affiliated Research Center, Inc.
    Huntsville, Alabama 35801, United States
  • Ruth A. Yates, MD
    Huntsville, Alabama 35801, United States
  • SunValley Arthritis Center Ltd
    Glendale, Arizona 85308-7100, United States
  • Alliance Dermatology and MOHS
    Phoenix, Arizona 85032, United States
  • BGPDS Dermatology
    Little Rock, Arkansas 72205, United States
  • Hull Dermatology, PA
    Rogers, Arkansas 72758, United States
  • Bakersfield Dermatology and Skin Cancer Medical Grp
    Bakersfield, California 93309, United States
  • T. Joseph Raoof, MD, Inc.
    Encino, California 91436, United States
  • Minarets Medical Group
    Fresno, California 93711, United States
  • Associates In Research, Inc.
    Fresno, California 93720, United States
  • Delta Dermatology Medical Group
    Inglewood, California 90301, United States
  • Fairmont Dermatology Medical Associates, Inc
    Lodi, California 95242, United States
  • Dermatology Associates
    Los Angeles, California 90045, United States
  • Elizabeth A. Abel, MD
    Mountain View, California 94040, United States
  • Dermatology Medical Group of Oxnard
    Oxnard, California 93030, United States
  • Kent Carson, MD
    San Jose, California 95123, United States
  • East Bay Psoriasis Treatment Center
    San Ramon, California 94583, United States
  • Clinical Research Specialists, Inc.
    Santa Monica, California 90404, United States
  • Healthcare Partners Medical Group
    Torrance, California 90503, United States
  • Skin Physicians and Surgeons Medical Group, Inc.
    Upland, California 91786, United States
  • Centennial Cosmetic Surgery and Dermatology
    Centennial, Colorado 80112, United States
  • Colorado Medical Research Center, Inc.
    Denver, Colorado 80210, United States
  • Meridian Skin Cancer Center
    Englewood, Colorado 80112, United States
  • Northern Colorado Allergy and Asthma Clinic
    Greeley, Colorado 80634, United States
  • Dermatology Associates Of Western Connecticut
    Danbury, Connecticut 06810, United States
  • George Washington University Medical Center
    Washington, District of Columbia 20037, United States
  • Aventura Medical Research Inc
    Aventura, Florida 33180, United States
  • Stephen N Horwitz, MD, PA
    Aventura, Florida 33180, United States
  • Brent M Schillinger, MD, PA
    Boca Raton, Florida 33433, United States
  • The Dermatology and Aesthetic Center
    Boca Raton, Florida 33486, United States
  • David Hecker, MD
    Boca Raton, Florida 33496, United States
  • Dermatology Associates and Research
    Coral Gables, Florida 33134, United States
  • North Florida Dermatology Associates, PA
    Jacksonville, Florida 32204, United States
  • Coastal Dermatology
    Jacksonville, Florida 32246, United States
  • Genesis Dermatology
    Jupiter, Florida 33458, United States
  • University of Miami Dept. of Dermatology and Cutaneous Surgery
    Miami, Florida 33136, United States
  • Park Avenue Dermatology
    Orange Park, Florida 32073, United States
  • Central Florida Dermatology Associates, Inc.
    Orlando, Florida 32806, United States
  • Dermatology Consultants of Broward
    Pembroke Pines, Florida 33028, United States
  • Dermatology Research by Dr. Gary L. Heller
    Pinellas Park, Florida 33781, United States
  • Clinical Research of Tampa Bay, Inc.
    Spring Hill, Florida 34609, United States
  • Atlanta Dermatology, Vein, and Research Center, LLC
    Alpharetta, Georgia 30005, United States
  • Emory University
    Atlanta, Georgia 30322, United States
  • Dermatology Specialists of West Georgia
    Carrollton, Georgia 30117, United States
  • East Metro Dermatology
    Conyers, Georgia 30012, United States
  • Dermatologic Surgery Specialists, Inc.
    Macon, Georgia 31217, United States
  • Northwest Georgia Dermatology
    Rome, Georgia 30165, United States
  • Gwinnett Clinical Research Center Inc.
    Snellville, Georgia 30078, United States
  • Toccoa Clinic Medical Associates
    Toccoa, Georgia 30577, United States
  • Queens Medical Center
    Honolulu, Hawaii 96813, United States
  • Alan Olmstead, MD
    Twin Falls, Idaho 83301, United States
  • Fox Valley Dermatology LTD
    Aurora, Illinois 60502, United States
  • Christie Clinic
    Champaign, Illinois 61820, United States
  • Northwestern University
    Chicago, Illinois 60611, United States
  • Danilo V. Del Campo
    Chicago, Illinois 60641, United States
  • Advanced Dermatology
    Lincolnshire, Illinois 60069, United States
  • Skin Care Center Of Southern Illinois
    Mt Vernon, Illinois 62864, United States
  • Schaumburg Dermatology
    Schaumburg, Illinois 60194, United States
  • Dermatology Center of Northwest Indiana
    Crown Point, Indiana 46307, United States
  • Three Rivers Dermatology
    Ft. Wayne, Indiana 46804, United States
  • Dermatology Associates, PC
    Indianapolis, Indiana 46240, United States
  • Investigators Research Group
    Indianapolis, Indiana 46254, United States
  • Dawes Fretzin Clinical Research Group, LLC
    Indianapolis, Indiana 46256, United States
  • The Dermatology Center PSC
    New Albany, Indiana 47150, United States
  • The Dermatology Center of Indiana
    Plainfield, Indiana 46168, United States
  • Randall Dermatology, PC
    West Lafayette, Indiana 47906, United States
  • University of Iowa Health Care
    Iowa City, Iowa 52242, United States
  • Kansas City Dermatology, PA
    Overland Park, Kansas 66215, United States
  • Kansas Medical Clinic
    Topeka, Kansas 66614, United States
  • Graves Gilbert Clinic
    Bowling Green, Kentucky 42101, United States
  • Derm Research, PLLC
    Louisville, Kentucky 40217, United States
  • Louisiana Dermatology Associates
    Baton Rouge, Louisiana 70806, United States
  • Dermatology and Advanced Aesthetics
    Lake Charles, Louisiana 70601, United States
  • Highland Clinic, APMC
    Shreveport, Louisiana 71105, United States
  • Washington Dermatology Center
    Bethesda, Maryland 20814, United States
  • Callender Skin and Laser Center
    Mitchellville, Maryland 20721, United States
  • Brigham and Womens' Hospital
    Boston, Massachusetts 02115, United States
  • Skin Care Physicians of Chestnut Hill
    Chestnut Hill, Massachusetts 02467, United States
  • Dermatology Associates
    Norwood, Massachusetts 02062, United States
  • Worcester Dermatology
    Worcester, Massachusetts 01608, United States
  • David Fivenson, MD Dermatology, PLLC
    Ann Arbor, Michigan 48103, United States
  • Great Lakes Research Group, Inc.
    Bay City, Michigan 48706, United States
  • Psoriasis and Eczema Treatment Center of Western Michigan PLLC
    Grand Rapids, Michigan 49503, United States
  • Somerset Skin Centre
    Troy, Michigan 48084, United States
  • M. Siegel, MD PC
    Waterford, Michigan 48328-3735, United States
  • Lloyd J. Cleaver, DO, LLC
    Kirksville, Missouri 63501, United States
  • Saint Louis University
    St. Louis, Missouri 63104, United States
  • Central Dermatology, PC
    St. Louis, Missouri 63117, United States
  • Jacquelyn B. Garrett
    St. Louis, Missouri 63136, United States
  • Karen E Forsman, MD Dermatology LLC
    St. Louis, Missouri 63141, United States
  • South Lincoln Dermatology
    Lincoln, Nebraska 68502, United States
  • Woodson Dermatology
    Las Vegas, Nevada 89128, United States
  • Nevada Center For Dermatology, Ltd
    Reno, Nevada 89511, United States
  • Skin Cancer and Dermatology Institute
    Reno, Nevada 89511, United States
  • Dartmouth-Hitchcock Medical Center
    Lebanon, New Hampshire 03756, United States
  • Nashua Dermatology Associates
    Nashua, New Hampshire 03062, United States
  • Nashua Dermatology
    Nashua, New Hampshire 03062, United States

Showing the first 100 of 182 sites.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 2, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00096928
Lead sponsor
Genentech, Inc.
First posted
Nov 18, 2004
Start date
Mar 2005
Completion
Oct 2009
Last update
Jul 2, 2015

Study contacts

Ivor Caro, M.D.
study director · Genentech, Inc.
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2011. You cannot join it, but the record below documents what was studied.

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