ClinicalTrials.gg
CompletedNCT00013819Updated Apr 14, 2015

Exposure, Dose, Body Burden and Health Effects of Lead

An observational study in Lead Poisoning, sponsored by National Institute of Environmental Health Sciences (NIEHS). Completed. Open to participants aged 17 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-04-14.

Sponsored by National Institute of Environmental Health Sciences (NIEHS) · Observational

Study type
Observational
Time perspective
Prospective
Enrollment
944
Ages
17 Years to 70 Years
Sex
All
01

Study summary

This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure, and the blood forming system. A total of 803 lead workers and 135 persons without occupational lead exposure are being studied in South Korea. Lead in the body is being assessed by measurement of blood lead, chelatable lead (an estimate of lead in the tissues), and lead in bone. Subjects are tested three times each over three years. Several genetic factors are also being assessed for the role they play in the health effects of lead. These genes are known to differ among individuals. We are interested to know whether different forms of the same genes can modify the effect lead has on health.

02

Conditions studied

  • Lead Poisoning

Keywords

  • lead poisoning
  • central nervous system
  • peripheral nervous system
  • occupational health
  • genetic susceptibility
03

In context

Lead Poisoning

27 studies on the registry are indexed under Lead Poisoning; 2 are open to participants now.

This study's enrollment of 944 is above the median of 350 across 14 observational studies indexed under Lead Poisoning.

Browse Lead Poisoning studies →

Lead sponsor

National Institute of Environmental Health Sciences (NIEHS) is the lead sponsor of 183 studies on the registry; 18 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
17 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Lead workers in South Korea in one of 26 specific lead-using facilities.

Population controls in South Korea.

05

Study design

Time perspective
Prospective
Enrollment
944 participants
06

Study locations

No study locations are listed for this record.

07

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Feb 1997, a primary completion of Feb 2001 and a completion of Feb 2001. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 29, 2001
First posted
Mar 30, 2001
Start
Feb 1997
Primary completionActual
Feb 2001
CompletionActual
Feb 2001
Last update
Apr 14, 2015
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 14, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00013819
First posted
Mar 30, 2001
Start date
Feb 1997
Primary completion
Feb 2001
Completion
Feb 2001
Last update
Apr 14, 2015
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2015. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion