An observational study in Albinism, Albinism, Ocular and Albinism, Oculocutaneous, sponsored by National Eye Institute (NEI). Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2008-03-04.
Sponsored by National Eye Institute (NEI) · Observational
To study the relationship between visual function and ocular (iris, retina/choroidal) pigmentation in patients with albinism and other hypomelanotic disorders. To identify the carrier state in relatives of patients with ocular albinism.
Visual function and ocular pigmentation are being studied in patients with albinism and other disorders associated with hypopigmentation. The degree of ocular pigmentation is assessed clinically by estimating the melanin content of the iris, retinal pigment epithelium, and choroid. Visual function is measured in the conventional manner to study central vision, and electrophysiological methods to detect a misrouting of the visual pathways. The purpose of this study is to document the visual deficit and the pigmentary changes of patients with albinism, to observe their natural course, and to determine whether misrouting of the visual pathways is present and is correlated with pigmentation.
17 studies on the registry are indexed under Albinism; 8 are open to participants now.
This study's enrollment of 130 is close to the median of 140 across 10 observational studies indexed under Albinism.
Browse Albinism studies →National Eye Institute (NEI) is the lead sponsor of 272 studies on the registry; 17 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 8 (100%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients have been recruited into the study by referral from an ophthalmologist or pediatrician.
Entrance into the study was dependent upon clinical evidence of decreased or absent pigmentation in skin, hair, and/or eyes.
The definition was purposefully broad to include the broad range of phenotype variations and clinical heterogeneity.
The purpose of the study id to be able to document iris and retina/choroidal pigmentation and correlated these finding with visual function.
The record gives a start of Jun 1976 and a completion of May 2000. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in May 1999. You cannot join it, but the record below documents what was studied.
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