Yale University: Stress Disorders, Post-Traumatic trials

The registry lists 28 Stress Disorders, Post-Traumatic studies with Yale University as lead sponsor. 5 are open to participants now and 9 have results posted.

Early Phase 1 2Phase 1 8Phase 2 8Phase 3 4Phase 4 1No phase 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Open-Label Psilocybin Study in Transdiagnostic PopulationRecruitingNCT06442423Phase 1
• Imaging Traumatic Stress and Alcohol Use Disorder With [18F]BavarostatRecruitingNCT06371404
• Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine ResponseRecruitingNCT05915013Phase 1
• The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal EffectsRecruitingNCT05786066Phase 2
• Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) ScanningRecruitingNCT01730781
• Imaging the Neuroimmune System in PTSDCompletedNCT04236986Phase 1Results posted
• Neurofeedback of Amygdala Activity for Post-traumatic Stress DisorderTerminatedNCT03574974Not applicableResults posted
• Intensive 7-day Treatment for PTSD Combining Ketamine With Exposure TherapyTerminatedNCT02727998Phase 2Results posted
• Oxytocin and Affect Processing in Posttraumatic Stress DisorderCompletedNCT02546570Phase 2Results posted
• Progesterone Effect on Individuals Diagnoses With AD and PTSD.CompletedNCT02187224Phase 2/3Results posted
• A Pilot Study Of Riluzole In Patients With Post Traumatic Stress Disorder (PTSD)CompletedNCT02019940Phase 1Results posted
• Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol DependenceCompletedNCT01847469Phase 2Results posted
• PET Imaging of mGLuR5 With Drug ChallengeCompletedNCT01691092Not applicableResults posted
• Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).CompletedNCT00744055Phase 3Results posted
• Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic PsychedelicsTerminatedNCT06624137
• Enhancing Week-long Psychological Treatment for PTSD With KetamineActive, not recruitingNCT05737693Phase 2
• Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress DisorderActive, not recruitingNCT05223829Phase 1
• FAAH Availability in Psychiatric Disorders: A PET StudyTerminatedNCT04404712Early Phase 1
• The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.WithdrawnNCT03752918Phase 1
• Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot TrialCompletedNCT03367533Phase 1
• Imaging SV2A in Mood DisordersActive, not recruitingNCT02734602Not applicable
• Examination of Glutamate and mGluR5 in Psychiatric DisordersCompletedNCT02727972
• Evaluation of the Child and Family Traumatic Stress InterventionCompletedNCT01031615Phase 1/2
• Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol DependenceCompletedNCT00923923Not applicable
• Effects of Paliperidone in Posttraumatic Stress Disorder (PTSD)WithdrawnNCT00766064Phase 4
• Effects of Duloxetine on Fear Conditioning in Posttraumatic Stress Disorder (PTSD)CompletedNCT00763178Early Phase 1
• Couples-based Behavioral Psychotherapy for Male Patients With Posttraumatic Stress Disorder and Alcohol DependenceWithdrawnNCT00622921Phase 2/3
• The Use of Anticonvulsants for Treatment of Patients With Alcohol Dependence and Post Traumatic Stress DisorderWithdrawnNCT00571246Phase 3