Washington University School of Medicine: Alzheimer Disease trials

The registry lists 24 Alzheimer Disease studies with Washington University School of Medicine as lead sponsor. 8 are open to participants now and 4 have results posted.

Phase 1 1Phase 2 7Phase 3 7No phase 15(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic PainRecruitingNCT06978166Not applicable
• A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic MutationRecruitingNCT06647498Phase 2/3
• Study to Understand Novel Biomarkers in Researching DementiaRecruitingNCT06547099
• Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-FluselenamylRecruitingNCT06439992
• Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1RecruitingNCT06129838
• A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic MutationRecruitingNCT05552157Phase 2/3
• F 18 T807 Tau PET Imaging in Dominantly Inherited Alzheimer's Network (DIAN Project)Enrolling by invitationNCT02414178
• Dominantly Inherited Alzheimer Network (DIAN)RecruitingNCT00869817
• Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic MutationTerminatedNCT06424236Phase 2/3Results posted
• Falls: A Marker of Preclinical ADCompletedNCT04949529Results posted
• Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.CompletedNCT04623242Phase 2/3Results posted
• Caregiver Speaks: A Technologically Mediated Storytelling InterventionCompletedNCT04103580Not applicableResults posted
• Implement and Test Visual Consent Template and ProcessTerminatedNCT06804837Not applicable
• DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's DiseaseActive, not recruitingNCT06384573Phase 3
• Fluselenamyl - Beta Amyloid PET Imaging for Alzheimer DiseaseActive, not recruitingNCT05731440
• R21 Roche: 3-Way Tau Tracers in ADActive, not recruitingNCT05464368Phase 1
• Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)Active, not recruitingNCT05269394Phase 2/3
• Returning Research Results That Indicate Risk of Alzheimer Disease Dementia to Healthy Participants in Longitudinal StudiesActive, not recruitingNCT04699786Not applicable
• Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) StudyActive, not recruitingNCT04685590Phase 2
• Connectomics in Psychiatric ClassificationCompletedNCT03967535
• CNS Tau Kinetics in Healthy Aging and Alzheimer's DiseaseCompletedNCT03938870
• Study to Evaluate Amyloid in Blood and Imaging Related to DementiaCompletedNCT03899844
• CNS and Plasma Amyloid-Beta Kinetics in Alzheimer's DiseaseCompletedNCT02021682
• Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001Active, not recruitingNCT01760005Phase 2/3