Vanderbilt University Medical Center: Insulin Resistance trials

The registry lists 10 Insulin Resistance studies with Vanderbilt University Medical Center as lead sponsor. 2 are open to participants now and 3 have results posted.

Early Phase 1 1Phase 1 6Phase 2 3No phase 2(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 DiabetesRecruitingNCT06609356Early Phase 1
• Physiologic and Functional Adaptations of Insulin Sensitive TissuesEnrolling by invitationNCT03407833
• A Study to Determine Iatrogenic Hyperinsulinemia's Contribution to Insulin Resistance and Endothelial Dysfunction in Type 1 DiabetesCompletedNCT04118374Not applicableResults posted
• CD36 in Nutrient Delivery and Its DysfunctionCompletedNCT03012386Phase 1/2Results posted
• Study of Sildenafil Citrate on Insulin Resistance in African AmericanCompletedNCT01334554Phase 1/2Results posted
• Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in ObesityActive, not recruitingNCT03318094Phase 1
• Autonomic Blockade and Endogenous Glucose ProductionWithdrawnNCT03028571Phase 1
• Racial Differences in Vagal Control of Glucose Homeostasis, Chronic StudyWithdrawnNCT03014323Phase 1
• Nutrition and Exercise Study to Understand Metabolic SyndromeCompletedNCT02899910Phase 2
• Ghrelin and Insulin ResistanceCompletedNCT00884494Phase 1