University of Virginia: Diabetes Mellitus, Type 1 trials

The registry lists 72 Diabetes Mellitus, Type 1 studies with University of Virginia as lead sponsor. 4 are open to participants now and 37 have results posted.

Early Phase 1 3Phase 1 1Phase 2 2No phase 66(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Impact of Obesity on Microvascular Insulin Action and Cardiorespiratory Fitness in Type 1 DiabetesRecruitingNCT07573228Not applicable
• Estimating Insulin Sensitivity in Pregnancies With Type 1 DiabetesEnrolling by invitationNCT07351318
• Evaluation of a Novel Insulin Sensitizer in People With Type 1 DiabetesRecruitingNCT07186660Phase 2
• Artificial Pancreas Technology to Reduce Glycemic Variability and Improve Cardiovascular Health in Type 1 DiabetesRecruitingNCT05653518Not applicable
• Neural-net Artificial Pancreas (NAP)CompletedNCT05876273Not applicableResults posted
• Hybrid Closed-Loop Control With Smart Prandial Insulin Dosing in Type 1 DiabetesCompletedNCT04878120Not applicableResults posted
• Diabetes Closed-Loop Project 6 (DCLP6): Fully Automated Closed-Loop Control in Type 1 Diabetes Using Meal AnticipationCompletedNCT04877730Not applicableResults posted
• Adaptive Biobehavioral Control (ABC) of Automated Insulin DeliveryCompletedNCT04784637Not applicableResults posted
• Fully Automated Closed Loop Control in Adolescents With Type 1 DiabetesCompletedNCT04545567Not applicableResults posted
• Adapting Diabetes Treatment Expert Systems to Patient in Type 1 DiabetesCompletedNCT04443153Not applicableResults posted
• Web-Based Simulation Tool For Self-Management Support In Type 1 Diabetes MellitusCompletedNCT04439903Not applicableResults posted
• Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD).CompletedNCT04094064Not applicableResults posted
• Safety of Artificial Pancreas Therapy in Preschoolers, Age 2-6CompletedNCT04084171Not applicableResults posted
• A Study of t:Slim X2 With Control-IQ TechnologyCompletedNCT03844789Not applicableResults posted
• Safety and Efficacy of Initializing the Control-IQ Artificial Pancreas System Using Total Daily InsulinCompletedNCT03804983Not applicableResults posted
• CloudConnect: Predictive And Retrospective Clinical Decision Support For Chronic Disease ManagementCompletedNCT03676465Not applicableResults posted
• The VRIF Trial: Hypoglycemia Reduction With Automated-Insulin Delivery SystemCompletedNCT03674281Not applicableResults posted
• The International Diabetes Closed Loop (iDCL) Trial: Clinical Acceptance of the Artificial Pancreas (DCLP3 Extension)CompletedNCT03591354Not applicableResults posted
• The International Diabetes Closed Loop (iDCL) Trial: Clinical Acceptance of the Artificial PancreasCompletedNCT03563313Not applicableResults posted
• CGM Use in Islet Transplant RecipientsCompletedNCT03427931Not applicableResults posted
• Artificial Pancreas and Remote Monitoring During a T1DM Youth Ski CampCompletedNCT03369067Not applicableResults posted
• A Pilot Test of t:Slim X2 With Control-IQ TechnologyCompletedNCT03368937Not applicableResults posted
• Efficacy of inControl Advice: A Decision Support System (DSS) for DiabetesCompletedNCT03093636Not applicableResults posted
• The International Diabetes Closed Loop (iDCL) Trial: Protocol 1CompletedNCT02985866Not applicableResults posted
• Closed-Loop Control in Young Children 5-8 Years Old Using DiAs PlatformCompletedNCT02750267Not applicableResults posted
• Project Nightlight: Efficacy and System Acceptance of Dinner/Night vs. 24hr Closed Loop ControlCompletedNCT02679287Not applicableResults posted
• USS Virginia Closed-Loop Versus SAP Therapy for Hypoglycemia Reduction in T1DCompletedNCT02302963Not applicableResults posted
• Diabetes Assistant (DiAs) Control-to-Range (CTR) Nocturnal Closed-Loop Camp StudyCompletedNCT01973413Not applicableResults posted
• Optimizing Closed-Loop Control of Type 1 Diabetes Mellitus in AdolescentsCompletedNCT01890954Not applicableResults posted
• Biobehavioral Mechanisms of Glucose VariabilityCompletedNCT01835964Not applicableResults posted
• Early Feasibility Study 2 of Outpatient Control-to-Range - Testing System EfficacyCompletedNCT01714505Not applicableResults posted
• Development of an Advisory System for Glycemic Control During the Menstrual Cycle in Patient With Type 1 DiabetesCompletedNCT01653210Results posted
• Feasibility Study of Closed Loop Control in Type 1 Diabetes Using Heart Rate Monitoring as an Exercise MarkerCompletedNCT01582139Not applicableResults posted
• Outpatient Control-to-Range: System and Monitoring TestingCompletedNCT01578980Not applicableResults posted
• A Clinical Study of the Performance of a Glucose Blinding Protein-Based Continuous Glucose Monitor (GBP CGM)CompletedNCT01469715Phase 2Results posted
• Insulin Sensitivity, Impaired Counterregulation, and Glucose VariabilityCompletedNCT01439672Not applicableResults posted
• Development of a Behavioral Observer for Type 1 Diabetes MellitusCompletedNCT01434030Not applicableResults posted
• Feasibility Study of a Modular Control to Range System in Type 1 Diabetes MellitusCompletedNCT01418703Not applicableResults posted
• Hypoglycemia Prevention After Exercise in Adolescent T1DM Patients Using a Control to Range SystemCompletedNCT01390259Not applicableResults posted
• Pilot Study of Closed-Loop Glucose Control in People With Type 1 Diabetes (BPK004)CompletedNCT00977808Not applicableResults posted
• Counter-Regulatory Impairment and the Effect of Microvascular Insulin Transfer in Type 1 Diabetes MellitusCompletedNCT00943787Not applicableResults posted
• InsuLearn Feasibility With Type 1 Diabetes Patients Under MDI TherapyCompletedNCT06411548Not applicable
• Effect of Postprandial Hyperglycemia on Vasculature in Type 1 Diabetes and Healthy AdultsCompletedNCT04730882
• Glycemic Profiles And Insulin Delivery Across The Menstrual Cycle In Women With Type 1 DiabetesCompletedNCT04665999
• Artificial Pancreas - Adolescent Physiology & Psychology Longitudinal EvaluationCompletedNCT04510506Not applicable
• Use of Closed Loop Insulin Delivery for Glucose Control in Patients With Insulin Dependent Diabetes Mellitus After Kidney TransplantationWithdrawnNCT04189510Not applicable
• Effect of GLP-1 on Microvascular Insulin Responses in Type 1 DiabetesWithdrawnNCT04133922Early Phase 1
• Study to Test Efficacy of Real-time Reminders on Apple Watch To Decrease Late or Missed Meal BolusesCompletedNCT03809858Not applicable
• Safety and Feasibility of an Insulin Sensitivity-Informed Bolus Calculator in Type 1 DiabetesCompletedNCT03709108Not applicable
• Glucagon Counterregulation in Type 1 DiabetesTerminatedNCT03547427Not applicable
• Exercise Activity-Based Bolus Decisions in Type 1 DiabetesCompletedNCT03394352Not applicable
• The Impact of Fitness and Mineralocorticoid Receptor Blockade on Vascular Dysfunction in Adults With Type 1 DiabetesCompletedNCT03174288Not applicable
• International Diabetes Closed Loop (iDCL) Trial: Research Site Training ProtocolCompletedNCT02844517Not applicable
• Insulin-Glucose-Glucagon Network: Defining a Type 1 Diabetes Progression IndexCompletedNCT02663661Not applicable
• BGAT (Blood Glucose Awareness Training) for Users Who Might Become PregnantCompletedNCT02508779Not applicable
• The Effect of Type 1 Diabetes on Pan-Arterial Vascular Function and Insulin Sensitivity in HumansCompletedNCT02490124
• Development of a Comprehensive AP Training Curriculum for AdultsCompletedNCT02434094
• Full Day and Night Closed-Loop With DiAs PlatformCompletedNCT02147860Not applicable
• Accuracy of Blood Glucose Detection by Diabetes Alert DogsStatus unknownNCT02126605
• Phase 2 Study of Adaptive Insulin Meal Supervisor (AIMS) in Adults With Type 1 Diabetes MellitusCompletedNCT01839370Not applicable
• Evaluation of a Simulation-Based Educational Tool for Personalized Feedback in Insulin Therapy ManagementTerminatedNCT01767831
• Early Feasibility Study 2 of Outpatient Control-to-Range - Testing System Efficacy (France)CompletedNCT01742741Not applicable
• Early Feasibility Study 2 of Outpatient Control-to-Range - Testing System Efficacy (Italy)CompletedNCT01727817Not applicable
• Identifying Driving Risk Factors in Type 1 Diabetes and Their Reduction Via Internet Program (DiabetesDriving.Com)CompletedNCT01563887Not applicable
• Pilot Study 1 of Outpatient Control-to-Range - System and Monitoring TestingCompletedNCT01470807Not applicable
• Feasibility Study of a Portable Artificial Pancreas System in Type 1 Diabetes Mellitus (T1DM) - PadovaCompletedNCT01447992Early Phase 1
• Feasibility Study of a Portable Artificial Pancreas System in Type 1 Diabetes Mellitus (T1DM) - MontpellierCompletedNCT01447979Early Phase 1
• Pramlintide Combined With Model Predictive Control AlgorithmTerminatedNCT01434862Not applicable
• The Impact of Fitness on Vascular Dysfunction in Adolescents With Type 1 DiabetesCompletedNCT01337947
• UVA Islet Cell Transplantation in Patients With Type I DiabetesStatus unknownNCT00605592Phase 1
• Feasibility and Efficacy of Delivering Blood Glucose Awareness Training Over the InternetCompletedNCT00327210Not applicable
• Blood Glucose Awareness Training for ParentsCompletedNCT00315991Not applicable