University of Texas Southwestern Medical Center: Depressive Disorder, Major trials

The registry lists 20 Depressive Disorder, Major studies with University of Texas Southwestern Medical Center as lead sponsor. 1 are open to participants now and 10 have results posted.

Phase 1 3Phase 2 5Phase 3 3Phase 4 5No phase 7(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Pregnenolone for Cannabis Use Disorder and DepressionNot yet recruitingNCT07685964Phase 1/2
• Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic TargetsCompletedNCT05046184Phase 2Results posted
• Development of Pregnenolone as a Treatment for DepressionCompletedNCT03645096Phase 1Results posted
• A Neurosteroid Intervention for Menopausal and Perimenopausal DepressionCompletedNCT03505905Phase 1/2Results posted
• Rapid Antidepressant Effects of LeucineTerminatedNCT03079297Phase 2Results posted
• Treating Caregiver Depression to Improve Childhood Asthma: Impact and MediatorsCompletedNCT02809677Not applicableResults posted
• Study Using Pregnenolone to Treat Bipolar DepressionCompletedNCT01409096Phase 4Results posted
• Time to Remission of Depressive Symptoms With Combined SSRI and RamelteonTerminatedNCT00642694Phase 3Results posted
• Treatment of Outpatients With Severe Asthma and Moderate or Severe Major Depressive DisorderCompletedNCT00621946Phase 4Results posted
• Aripiprazole Augmentation of SSRI Therapy in Treatment Refractory DepressionCompletedNCT00608543Phase 4Results posted
• A Pilot Study of Citicoline add-on Therapy in Patients With Bipolar Disorder or Major Depressive Disorder and Amphetamine Abuse or DependenceCompletedNCT00377299Not applicableResults posted
• Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With DepressionActive, not recruitingNCT05966532
• Predictors of Depression Treatment Response to ExerciseCompletedNCT02583867Phase 3
• A Health Intervention to Prevent Depression Hepatitis C PatientsTerminatedNCT01890083Phase 2/3
• Electronic-Measurement Based Care for Major Depressive DisorderWithdrawnNCT01583998Not applicable
• A Comprehensive Intervention for Diabetes and Comorbid Depression in Primary CareCompletedNCT00939250Phase 4
• Assessment of Cognitive Functioning Before and After Treatment With DuloxetineCompletedNCT00933439Not applicable
• Using Neuroimaging to Investigate Major Depressive DisorderCompletedNCT00781677
• Impact of Caregiver Depression on Asthma in the ChildCompletedNCT00223288
• Pregnenolone Trial for Depression in Bipolar Disorders or Recurrent Major Depressive Disorder With Substance AbuseCompletedNCT00223197Phase 4