University of North Carolina, Chapel Hill: Depressive Disorder trials

The registry lists 30 Depressive Disorder studies with University of North Carolina, Chapel Hill as lead sponsor. 1 are open to participants now and 17 have results posted.

Phase 2 4Phase 3 1Phase 4 4No phase 22(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Examining the Effects of Estradiol on Neural and Molecular Response to RewardRecruitingNCT05282277Phase 4
• Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS)TerminatedNCT06979154Not applicableResults posted
• Augmenting Single-session Behavioral Activation (BA) With Delta-beta Transcranial Alternating Current Stimulation (tACS) for the Treatment of DepressionCompletedNCT05693922Not applicableResults posted
• Dynamic Neural Mechanisms of Brexanolone-induced Antidepressant Effects in Postpartum DepressionCompletedNCT05543746Results posted
• Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With AnhedoniaCompletedNCT05084924Not applicableResults posted
• iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of TreatmentCompletedNCT04485455Not applicableResults posted
• LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLETerminatedNCT04141046Not applicableResults posted
• A Pilot Trial of Perinatal Depression Treatment in HIV Infected WomenCompletedNCT04094870Phase 4Results posted
• Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine ModelCompletedNCT04051320Phase 2Results posted
• Mechanism of Action of tACS for the Treatment of MDDCompletedNCT03994081Not applicableResults posted
• Effects of a Tissue Selective Estrogen Complex (TSEC) on Depression and the Neural Reward System in the Perimenopause"CompletedNCT03740009Phase 4Results posted
• Single Session of tACS in a Depressive EpisodeCompletedNCT03449979Not applicableResults posted
• Transcranial Alternating Current Stimulation for Major Depressive DisorderCompletedNCT02339285Not applicableResults posted
• Perimenopausal Effects of Estradiol on Reward ResponsivenessCompletedNCT02255175Phase 4Results posted
• Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and ParturitionCompletedNCT01762943Not applicableResults posted
• Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and AdolescentsCompletedNCT01731119Phase 2Results posted
• Perimenopausal Estrogen Replacement Therapy StudyCompletedNCT01308814Phase 2/3Results posted
• Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) StudyCompletedNCT01269710Results posted
• Psychotherapy Feasibility Pilot of the Carolina Recovery From Depression ProtocolCompletedNCT06590038Not applicable
• Brain Network Dynamics of Depression During Esketamine TreatmentCompletedNCT06012916
• Project SOAR-Mental Health Malawi: Depression and HIV IntegrationCompletedNCT03555669Not applicable
• Technology Enhanced Behavioral Activation Treatment for Substance UseCompletedNCT02707887Not applicable
• CID 0911 - Adaptation of A Depression Treatment Intervention for HIV Patients in CameroonCompletedNCT02156622
• Determining Relationships Among Maternity Stress & SleepCompletedNCT02133963
• Study of Exposure to Stress, Postpartum Mood, Adverse Life Events, and Hormonal Function Among Latinas (SEPAH Latina)CompletedNCT01912833
• Behavioral Depression Treatment for African American HIV-infected Substance UsersCompletedNCT01351454Not applicable
• Treatment for Depression Among HIV-Infected YouthCompletedNCT01049789Not applicable
• Improving Representative Payeeship for People With Psychiatric Disabilities and Their FamiliesCompletedNCT00924976Not applicable
• Brain Imaging of Psychotherapy for DepressionCompletedNCT00609453Not applicable
• Reducing Symptoms of Depression in Low-Income MothersCompletedNCT00074789Phase 2