University of Florida: Glioblastoma trials
The registry lists 15 Glioblastoma studies with University of Florida as lead sponsor. 3 are open to participants now and 3 have results posted.
Phase 1 8Phase 2 5No phase 2(a study in two phases counts in both)
Studies
Open to participants first, then studies with results posted, then the rest; newest registration first within each.
- IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)Not yet recruitingNCT06946680Phase 1
- OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd TrialRecruitingNCT06558214Phase 2
- A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)RecruitingNCT04573140Phase 1
- Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)Active, not recruitingNCT03405792Phase 2Results posted
- TTFields and Pulsed Bevacizumab for Recurrent GlioblastomaTerminatedNCT02663271Phase 2Results posted
- Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma MultiformeCompletedNCT02465268Phase 2Results posted
- Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade GliomaActive, not recruitingNCT07031765Phase 1
- RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)Active, not recruitingNCT06389591Phase 1
- IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult GlioblastomaActive, not recruitingNCT05353530Phase 1
- Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM)Active, not recruitingNCT05120284Phase 2
- RENEW: Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients.TerminatedNCT04963413Phase 1
- NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma MultiformeTerminatedNCT01954576Not applicable
- Peptide Vaccine for Glioblastoma Against Cytomegalovirus AntigensWithdrawnNCT01854099Phase 1
- Laboratory Study of Early Tumor Markers in the Peripheral Blood of Glioblastoma Multiforme PatientsCompletedNCT01135875
- Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain TumorsCompletedNCT01111097Phase 1