University of Chicago: Carcinoma, Squamous Cell trials

The registry lists 18 Carcinoma, Squamous Cell studies with University of Chicago as lead sponsor. 4 are open to participants now and 8 have results posted.

Phase 1 5Phase 2 13No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Trial of Locoregionally Advanced Squamous Cell Carcinoma of The Head and NeckNot yet recruitingNCT07346196Phase 2
• Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCCRecruitingNCT06912087Phase 1
• Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial TreatmentRecruitingNCT06669572Phase 2
• Personalized, Adaptive Treatment for Locally Advanced Head and Neck CancerRecruitingNCT06005324Phase 1
• De-Escalation Therapy for Human Papillomavirus Negative DiseaseCompletedNCT03944915Phase 2Results posted
• Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck CancerCompletedNCT03107182Phase 2Results posted
• BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck CancerTerminatedNCT02706691Phase 2Results posted
• Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal CancerCompletedNCT02258659Phase 2Results posted
• PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck CancerCompletedNCT01816984Phase 1/2Results posted
• Study in Locally Advanced Squamous Cell Carcinoma of Head and NeckTerminatedNCT01133678Phase 2Results posted
• Cetuximab and Lenalidomide in Head and NeckCompletedNCT01133665Phase 2Results posted
• Phase II Study of Skin Toxicity Dosing of IRESSA (Gefitinib) in Squamous Cell Carcinoma of the Head and NeckCompletedNCT00519077Phase 2Results posted
• Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal CancerCompletedNCT04572100Phase 1
• PROGRESS Trial - Prophylactic Gabapentin for Relief of Symptoms and Improved SwallowingWithdrawnNCT03423264Phase 2
• Neoadjuvant Pembrolizumab + Epacadostat Prior to Curative Surgical Care for Squamous Cell Carcinoma of the Head and NeckWithdrawnNCT03325465Phase 2
• Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA Oropharyngeal CancerTerminatedNCT01949740
• Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck CancerCompletedNCT01847326Phase 1
• A Phase II Study of 250-mg ZD1839 Monotherapy in Recurrent or Metastatic or Both Recurrent and Metastatic Squamous Cell CarcinomaCompletedNCT01185158Phase 2