University of Alabama at Birmingham: Glioma trials

The registry lists 10 Glioma studies with University of Alabama at Birmingham as lead sponsor. 4 are open to participants now and 5 have results posted.

Early Phase 1 3Phase 1 3Phase 2 3No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Multiparametric Metabolic and Hypoxic PET/MRI Imaging Substudy in GliomasNot yet recruitingNCT07778979Early Phase 1
• Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade GliomaNot yet recruitingNCT07521657Phase 2
• MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain TumorsNot yet recruitingNCT05676489Early Phase 1
• Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade GliomaRecruitingNCT05632562Early Phase 1
• A Phase II Trial of Poly-ICLC for Low-Grade GliomasTerminatedNCT04544007Phase 2Results posted
• Trial of C134 in Patients With Recurrent GBMCompletedNCT03657576Phase 1Results posted
• Image-Based Quantitative Assessment of Acute Radiation-Induced Changes in GliomaTerminatedNCT03168919Not applicableResults posted
• Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant GliomaActive, not recruitingNCT02062827Phase 1Results posted
• Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade GliomasCompletedNCT01158651Phase 2Results posted
• Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)TerminatedNCT06193174Phase 1