University Medical Center Groningen: Heart Failure trials

The registry lists 29 Heart Failure studies with University Medical Center Groningen as lead sponsor. 9 are open to participants now and 4 have results posted.

Phase 2 5Phase 3 3Phase 4 1No phase 21(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• AV Nodal Ablation With Conduction System Pacing Versus Cardiac Resynchronization for Symptomatic Heart Failure Patients With Atrial FibrillationNot yet recruitingNCT07604727Not applicable
• Dilated Cardiomyopathy - Unknown Therapeutic Risk Reduction by Contempary Medication and Implantable Cardioverter-Defibrillators (DUTCH-ICD)Not yet recruitingNCT07415642Not applicable
• Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)RecruitingNCT07304817Phase 2
• Effectiveness and Safety of Uptitration of Guideline Directed MEdical Therapy in Heart Failure With Reduced Ejection Fraction With Limited Kidney Function AssessmentsNot yet recruitingNCT07275437Not applicable
• Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)RecruitingNCT07269366Not applicable
• Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart FailureRecruitingNCT06514820
• Bariatric Surgery Evaluation and Assessment of Treatment Efficacy - Intervention TrialRecruitingNCT06065124Not applicable
• Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal StudyRecruitingNCT05851053
• Value of Intense Phenotyping in Heart Failure With Preserved Ejection FractionRecruitingNCT05479669
• Pragmatic Urinary Sodium-based Treatment algoritHm in Acute Heart FailureCompletedNCT04606927Not applicableResults posted
• Effects of Empagliflozin on Clinical Outcomes in Patients With Acute Decompensated Heart FailureCompletedNCT03200860Phase 2Results posted
• Sildenafil in HFpEF (Heart Failure With Preserved Ejection Fraction) and PHCompletedNCT01726049Phase 3Results posted
• Metformin to Reduce Heart Failure After Myocardial InfarctionCompletedNCT01217307Phase 2/3Results posted
• Ablation in Patients With HF and Symptomatic AF: PULVERISE-AF-CRTWithdrawnNCT05760833Not applicable
• Oxidative Skeletal Muscle Metabolism in Chronic Heart Failure Patients With and Without Iron DeficiencyStatus unknownNCT05750940
• Cardiac Metabolic Profiling in the Fed StateStatus unknownNCT05460572Not applicable
• The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKDActive, not recruitingNCT05374291Phase 3
• Effects of a Single Oral Dose of KETone Ester ON Exercise Performance in Patients With Chronic Heart FailureCompletedNCT05348460Not applicable
• PErirenal Adipose Tissue and RenaL Hemodynamics in Patients With Heart Failure With Preserved Ejection FractionStatus unknownNCT05219188
• Digoxin Evaluation in Chronic Heart Failure: Investigational Study In Outpatients in the NetherlandsCompletedNCT03783429Phase 4
• Treatment of Central Sleep Apnoea in Patients With Heart Failure With Nasal High Flow Therapy (nHFT)TerminatedNCT03085641Not applicable
• A Combined Transvenous and Epicardial Lead Placement Procedure for Implantation of Cardiac Resynchronization Devices: a Feasibility Study.Status unknownNCT02247817Not applicable
• Ventricular Tachyarrhythmia Detection by Implantable Loop Recording in Patients With Heart Failure and Preserved Ejection FractionCompletedNCT01989299
• Brain Function and Perfusion in Patients With Heart FailureStatus unknownNCT01756014
• Markers and Response to Cardiac Resynchronization TherapyCompletedNCT01519908
• Study to Investigate the Effects of Vitamin D Administration on Plasma Renin Activity in Patients With Stable Chronic Heart FailureCompletedNCT01092130Phase 2
• Paracrine Mechanisms of Bone Marrow Stem Cell Signalling in Chronic Heart FailureStatus unknownNCT01086787
• Safety and Efficacy Study of Add On Aliskiren in Patients With Heart Failure and Renal ImpairmentTerminatedNCT00881439Phase 2
• Sympathetic Innervation of the Heart and Cardiac Resynchronization Therapy(CRT)WithdrawnNCT00567645