UNC Lineberger Comprehensive Cancer Center: Endometrial Neoplasms trials

The registry lists 16 Endometrial Neoplasms studies with UNC Lineberger Comprehensive Cancer Center as lead sponsor. 5 are open to participants now and 4 have results posted.

Early Phase 1 4Phase 1 2Phase 2 4Phase 3 1No phase 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Assessing Survival Outcomes With Checkpoint Inhibition ExteNded vs Discontinued in Endometrial CancerNot yet recruitingNCT07867002Phase 3
• Multimedia Aid for Genetic Testing in Gynecologic OncologyRecruitingNCT07084168Not applicable
• Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial CancerNot yet recruitingNCT07078838Phase 2
• Tirzepatide in Obesity-Driven Endometrial CancerRecruitingNCT07065552Early Phase 1
• ONC201 and Atezolizumab in Obesity-Driven Endometrial CancerRecruitingNCT05542407Phase 1
• High Intensity Interval Training in Endometrial CancerCompletedNCT04025229Not applicableResults posted
• MOtiVating Endometrial Cancer Survivors With Activity Monitors and Tailored FeedbackCompletedNCT03820024Not applicableResults posted
• Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical PatientsCompletedNCT02035787Phase 2Results posted
• Trisenox® in Women With Metastatic Endometrial CancerTerminatedNCT01184053Phase 2Results posted
• Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer SurvivorsCompletedNCT06171945Not applicable
• 18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone TherapyWithdrawnNCT05483023Phase 2
• Multimedia Aid Gynecologic Counseling and ConsentCompletedNCT03899441Not applicable
• Window of Opportunity Pilot Study of Pembrolizumab in Obesity-driven Endometrial CancerTerminatedNCT03694834Early Phase 1
• A Pre-Op Window Study Evaluating Anti-Proliferative Effects of Atorvastatin on the EndometriumCompletedNCT02767362Early Phase 1
• Preoperative Window Study of Metformin for the Treatment of Endometrial CancerCompletedNCT01911247Early Phase 1
• Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal WomenCompletedNCT00099008Phase 1