UNC Lineberger Comprehensive Cancer Center: Breast Neoplasms trials

The registry lists 72 Breast Neoplasms studies with UNC Lineberger Comprehensive Cancer Center as lead sponsor. 22 are open to participants now and 11 have results posted.

Early Phase 1 4Phase 1 7Phase 2 21No phase 42(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Pharmacologic Therapies to Mitigate Radiation- Associated Heart DiseaseRecruitingNCT07685938Phase 2
• Nutrition Awareness Among Women With Non-Metastatic Breast CancerRecruitingNCT07389967Not applicable
• Evolutionary Clinical Trial for Novel Biomarker-Driven TherapiesRecruitingNCT07340541Phase 2
• Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase ExerciseRecruitingNCT07313306Not applicable
• Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast CancerRecruitingNCT07276880Phase 2
• Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) ImagingRecruitingNCT07225114Phase 2
• Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer StudyRecruitingNCT07214610
• PREDICT-RD: ctDNA Surveillance in TNBC With Residual DiseaseRecruitingNCT07069595Phase 2
• Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast CancerRecruitingNCT07025785Not applicable
• Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)RecruitingNCT06902311Phase 2
• PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and SurvivalRecruitingNCT06896162Not applicable
• VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer PatientsRecruitingNCT06878547
• Promoting Resilience in Women With Breast Cancer (PRISM -MBC)RecruitingNCT06855654Not applicable
• BREAST Choice Decision Tool R21 - AIM2RecruitingNCT06817226Not applicable
• A Novel Approach Utilizing Organ Specific Age ProteomicsRecruitingNCT06789653
• Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast CancerRecruitingNCT06727773Phase 2
• Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T CellsRecruitingNCT06347068Phase 1
• UNC Pleural Fluid RegistryRecruitingNCT05620329
• Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After LumpectomyRecruitingNCT05472792Phase 2
• Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among CliniciansRecruitingNCT05440929
• Harnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCARecruitingNCT03769415Not applicable
• Correlation of Molecular Markers With Response to Therapy and Breast Cancer BehaviorRecruitingNCT01000883
• PET/MR in Surgical Planning for Breast CA Treated With Neoadj ChemoTerminatedNCT04149353Not applicableResults posted
• 3-D Super Resolution Ultrasound Microvascular ImagingTerminatedNCT04136912Phase 2Results posted
• ARFI, VisR and DDAI Ultrasound for Improving Discrimination of Malignant and Unresponsive Breast CancerCompletedNCT03785782Results posted
• Study Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast CancerCompletedNCT02768701Phase 2Results posted
• A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain MetastasesCompletedNCT01305941Phase 2Results posted
• Studying Blood Samples From Women With Breast Cancer or Ductal Carcinoma In Situ Who Are Receiving TamoxifenCompletedNCT00764322Phase 2Results posted
• Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Patients With Locally Recurrent or Metastatic Breast CancerCompletedNCT00266110Phase 2Results posted
• Cetuximab + / - Carboplatin for Estrogen Receptor-Negative, Progesterone Receptor-Negative Metastatic Breast CancerCompletedNCT00232505Phase 2Results posted
• Radiation Therapy During Surgery in Treating Older Women With Invasive Breast CancerCompletedNCT00182728Not applicableResults posted
• Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Women With Locally Recurrent or Metastatic Breast CancerTerminatedNCT00088985Phase 2Results posted
• Multimodality Treatment for Women With Stage II, Stage III, or Stage IV Breast CancerCompletedNCT00006110Phase 2Results posted
• Dissemination of BREASTChoice AIM1-BCompletedNCT07396766Not applicable
• Adaptation of a Values Assessment ToolCompletedNCT07068477Not applicable
• VisR for Noninvasively Interrogating Stromal Collagen Organization as a Breast Cancer Biomarker: Evaluation of Compression in Control SubjectsCompletedNCT06547034
• Mobile Health App to Promote Participation of Black Women in Breast Cancer Clinical TrialsCompletedNCT06361056Not applicable
• Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer SurvivorsCompletedNCT06171945Not applicable
• The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer TreatmentCompletedNCT06096623
• Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary TreatmentActive, not recruitingNCT05926024
• Assessing Functional Status Needs Via PRO Measures for Pts With Metastatic Breast CancerCompletedNCT05755347
• Comparison of CE-DBT and MRI in Patients With Known Breast LesionsTerminatedNCT05754749Early Phase 1
• Metastatic Breast Cancer-Specific Prognostic ToolCompletedNCT05574478
• Transitioning Care: Perspectives of Older Women With Early Breast Cancer on Current Telemedicine ModalitiesCompletedNCT04990934
• Patient-centered Communication About Healthy Weight in Early Breast CancerCompletedNCT04504201
• LCCC1931:Post-treatment Intervention in Women With Breast Cancer (70y/o+)CompletedNCT04292847
• Parsaclisib in Newly Diagnosed Stage I-IIIC Triple Negative or HER2+ Breast CancerWithdrawnNCT04142554Phase 1
• Impact of Home-based Aerobic and Strength Exercises During Chemotherapy for Early Breast Cancer on Biomarkers of AgingCompletedNCT03761706Not applicable
• Window of Opportunity Trial of Entinostat in Patients With Newly Diagnosed Stage I-IIIC,TNBCTerminatedNCT03361800Early Phase 1
• Feasibility of an 8-week Tai Chi Chuan Intervention for Breast Cancer SurvivorsCompletedNCT03196037Not applicable
• Plasma Circulating Tumor DNA Analyses in ER+ Metastatic Breast CancerWithdrawnNCT03161834
• Physical Activity to Maintain Quality of Life and Physical Function in Women With Metastatic Breast Cancer: a Pilot StudyCompletedNCT02682836Not applicable
• Impact of Physical Activity on Biomarker of Aging and Body Composition Among Breast Cancer Survivors Age 65 and OlderCompletedNCT02328313Not applicable
• The Impact of a Physical Activity Program on Biomarkers of Aging During Chemotherapy for Breast CancerCompletedNCT02167932
• The Use of Smart Scales for Weight Gain Prevention in African American Breast Cancer SurvivorsCompletedNCT02030353Not applicable
• Defining the HER2 Positive (+) Breast Cancer Kinome Response to Trastuzumab, Pertuzumab, Combination Trastuzumab +Pertuzumab, or Combination Trastuzumab + LapatinibCompletedNCT01875666Early Phase 1
• Assessment of Ability of Breath Hold for Left-sided Breast Cancer Radiation Therapy to Reduce Side Effects to HeartCompletedNCT01849614
• Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Known Breast LesionsCompletedNCT01773850
• Patient Preferences for Breast Reconstruction After MastectomyCompletedNCT01488357
• Defining the Triple Negative Breast Cancer Kinome Response to GSK1120212CompletedNCT01467310Early Phase 1
• Study of the P16 Gene as a Predictor of Myelosuppression in Breast Cancer PatientsCompletedNCT01305954
• Study of BKM120 or BYL719 and Capecitabine in Patients With Metastatic Breast CancerCompletedNCT01300962Phase 1
• Mammography Reminders for Encouraging Women to Undergo Regular Mammography Screenings for Breast CancerCompletedNCT01148875
• Biomarkers in Blood Samples From Older Breast Cancer SurvivorsCompletedNCT01138345
• Trastuzumab and External Beam Radiation Therapy in Treating Women With Stage III or Stage IV Breast CancerCompletedNCT00943410Phase 2
• Effect of Aprepitant on Cyclophosphamide Pharmacokinetics in Patients With Breast CancerCompletedNCT00719173Phase 1
• Lapatinib and Radiation Therapy in Treating Patients With Locally Recurrent or Chemotherapy-Refractory Locally Advanced or Metastatic Breast CancerCompletedNCT00379509Phase 1
• Using Magnetic Resonance Spectroscopy With MRI to Non-invasively Determine Breast Cancer Extent of DiseaseWithdrawnNCT00312637Not applicable
• Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast CancerCompletedNCT00237627Phase 1/2
• Molecular Marker Profiling of Axillary Lymph Nodes in Predicting Response in Patients With Locally Advanced or Metastatic Breast Cancer Who Are Undergoing Chemotherapy Followed By SurgeryCompletedNCT00233974Phase 2
• Capecitabine, Paclitaxel, and Trastuzumab in Treating Patients With Metastatic Breast CancerCompletedNCT00006108Phase 1/2
• High-Dose Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Metastatic Breast CancerCompletedNCT00003392Phase 2