UCB S.A.: Parkinson Disease trials

The registry lists 45 Parkinson Disease studies with UCB S.A. as lead sponsor. 0 are open to participants now and 30 have results posted.

Phase 1 7Phase 2 5Phase 3 19Phase 4 8No phase 6(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• An Extension Study to Evaluate the Long-Term Efficacy, Safety and Tolerability of Minzasolmin (UCB0599) in Study Participants With Parkinson's DiseaseTerminatedNCT05543252Phase 2Results posted
• A 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's DiseaseCompletedNCT04658186Phase 2Results posted
• Study to Evaluate the Impact of Using Wearable Devices in Addition to Standard Clinical Practice on Parkinson´s Subject Symptoms ManagementCompletedNCT03103919Phase 4Results posted
• A Study to Compare the Adhesiveness of 2 Different Rotigotine Patches Used for the Treatment of Parkinson's DiseaseCompletedNCT02230904Phase 1Results posted
• Trial to Evaluate The Efficacy Of Rotigotine on Parkinson's Disease-Associated Motor Symptoms And ApathyCompletedNCT01782222Phase 4Results posted
• Study to Evaluate the Efficacy of Rotigotine on Parkinson's Disease-Associated PainCompletedNCT01744496Phase 4Results posted
• A Phase 3b, Open-Label, Safety and Efficacy Study of Rotigotine as Add-On Therapy With Low Doses of Pramipexole or Ropinirole in Patients With Advanced Parkinson's DiseaseCompletedNCT01723904Phase 3Results posted
• A Phase 4, Open-label Study to Assess the Feasibility and Efficacy on Motor and Non-motor Symptoms of Switching From Pramipexole or Ropinirole to Rotigotine Transdermal Patch in Subjects With Advanced Idiopathic Parkinson's DiseaseCompletedNCT01711866Phase 4Results posted
• Rotigotine Versus Placebo As Double Blind Study To Evaluate The Efficacy In Early Stage Idiopathic Parkinson's Disease PatientsCompletedNCT01646268Phase 3Results posted
• Rotigotine Versus Placebo, A Study To Evaluate The Efficacy In Advanced Stage Idiopathic Parkinson's Disease PatientsCompletedNCT01646255Phase 3Results posted
• Observational Study With Neupro® to Evaluate the Patient´s Perception of Pain Associated With Parkinson´s DiseaseCompletedNCT01606670Results posted
• Effect of Rotigotine on Motor Symptoms in Patients With Advanced Parkinson's Disease (PD) With Motor Fluctuations and Symptoms of Gastrointestinal DysfunctionTerminatedNCT01536015Phase 3Results posted
• Rotigotine Versus Placebo to Evaluate the Efficacy on Depressive Symptoms in Idiopathic Parkinson's Disease PatientsCompletedNCT01523301Phase 4Results posted
• Sleep Efficiency Assessed by Polysomnography (PSG Sleep Lab Testing) in Advanced Parkinson's DiseaseTerminatedNCT01519882Phase 4Results posted
• Caregivers' and Physicians' Treatment Preference in Parkinson Patients Treated With Neupro® Requiring Caregiver SupportCompletedNCT01330290Results posted
• Placebo-controlled Study in Patients With Parkinson's Disease to Evaluate the Effect of Rotigotine on Non-motor SymptomsCompletedNCT01300819Phase 4Results posted
• Change in Gastrointestinal Complaints After Switch From Oral Parkinson's Disease Treatment to Neupro® Transdermal PatchCompletedNCT01159691Results posted
• Transdermal Rotigotine User Surveillance StudyCompletedNCT00599339Results posted
• An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Early-Stage Parkinson's DiseaseCompletedNCT00599196Phase 3Results posted
• A Trial of Neupro® (Rotigotine Transdermal Patch) in Patients With Parkinson's Disease Undergoing SurgeryCompletedNCT00594464Phase 4Results posted
• An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Advance-Stage Parkinson's DiseaseCompletedNCT00594386Phase 3Results posted
• An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Early-Stage Parkinson's Disease.CompletedNCT00594165Phase 3Results posted
• Safety and Tolerability Trial of Switching From Ropinirole to RotigotineCompletedNCT00593606Phase 3Results posted
• Trial to Assess Parkinson's Disease (PD) Symptom Control to Four Doses of Rotigotine in a Transdermal PatchCompletedNCT00522379Phase 3Results posted
• Long-term Extension of RECOVER- Long-term Effect of the 24h Transdermal Delivery of Rotigotine in Subjects With Idiopathic Parkinson's DiseaseTerminatedNCT00519532Phase 3Results posted
• An Open-Label Extension Trial to Assess the Safety and Tolerability of Long Term Treatment of Rotigotine in Subjects With Idiopathic Parkinson's DiseaseCompletedNCT00505687Phase 3Results posted
• An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Advanced-Stage Parkinson's DiseaseCompletedNCT00501969Phase 3Results posted
• Randomized Evaluation of the 24-Hour Coverage: Efficacy of RotigotineCompletedNCT00474058Phase 3Results posted
• Efficacy, Safety and Tolerability of Rotigotine Nasal Spray for the Acute Treatment of Parkinson SymptomsCompletedNCT00296192Phase 2Results posted
• Cardiac Effects of Rotigotine Transdermal System in Subjects With Advanced-stage Idiopathic Parkinson's DiseaseCompletedNCT00292227Phase 1Results posted
• A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of UCB0022 in Study Participants With Advanced Parkinson's DiseaseCompletedNCT06055985Phase 2
• A Study to Test the Safety, Tolerability, and Pharmacokinetics of UCB0599 in Healthy Study Participants and Patients With Parkinson's Disease (PD)CompletedNCT04875962Phase 1
• A Study to Test the Safety, Tolerability, and Blood Levels of UCB0022 in Healthy Participants and Participants With Parkinson's DiseaseCompletedNCT04867642Phase 1
• A Safety and Pharmacokinetics Study of UCB7853 in Healthy Study Participants and Study Participants With Parkinson's Disease (PD)CompletedNCT04651153Phase 1
• Evaluating the Effectiveness of Neupro® (Rotigotine) and L-dopa Combination Therapy in Patients With Parkinson's DiseaseCompletedNCT02227355
• Trial to Evaluate the Pharmacokinetics, Safety, and Tolerability of Rotigotine in Healthy Korean SubjectsCompletedNCT01964573Phase 1
• Non-interventional, Retrospective, Multi-center Study to Evaluate Non-motor Symptoms in Advanced Parkinson Disease (PD) Patients Already Treated With RotigotineCompletedNCT01504529
• Study to Compare Adhesiveness of Two Different Rotigotine Patch FormulationsCompletedNCT01338896Phase 1
• Rotigotine Patch in Subjects With Advanced Stage, Idiopathic Parkinson's Disease Who Are Not Well Controlled on LevodopaCompletedNCT00244387Phase 3
• A Trial to Compare the Efficacy of Rotigotine Transdermal Patch to That of Ropinirole on Early Morning Motor Impairment and Sleep Disorders in Subjects With Early-Stage, Idiopathic Parkinson's DiseaseCompletedNCT00243971Phase 3
• A Trial to Evaluate the Effects of Rotigotine Transdermal Patch on Early Morning Motor Impairment and Sleep Disorders Idiopathic Parkinson's DiseaseCompletedNCT00243945Phase 3
• A Trial To Assess Switching From Ropinirole, Pramipexole Or Cabergoline To The Rotigotine Transdermal System In Idiopathic Parkinson's DiseaseCompletedNCT00242008Phase 3
• Levetiracetam Treatment in Adult Subjects With Parkinson's Disease Experiencing Troublesome DyskinesiasCompletedNCT00160576Phase 2
• A Single Center, Randomized, Double-blind, Crossover Pilot Trial Comparing the Onset of Action of Parcopa™ With Sinemet® in Subjects With Stable Parkinson's DiseaseCompletedNCT00139880Phase 3
• A Multicenter, Open-label Trial to Assess Subject Preference of PARCOPA, Carbidopa/Levodopa Orally Disintegrating Tablets, Compared to Conventional Carbidopa/Levodopa Tablets in Subjects With Stable Parkinson's DiseaseCompletedNCT00139867Phase 3