U.S. Army Medical Research and Development Command: Dengue trials

The registry lists 16 Dengue studies with U.S. Army Medical Research and Development Command as lead sponsor. 0 are open to participants now and 8 have results posted.

Phase 1 13Phase 2 7(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Phase I/II Trial of a Tetravalent Live Attenuated DEN Vaccine in Flavivirus Antibody Naive ChildrenCompletedNCT01843621Phase 1/2Results posted
• A Two-dose Primary Vaccination Study of a Tetravalent Dengue Virus Purified Inactivated Vaccine vs. Placebo in Healthy AdultsCompletedNCT01666652Phase 1Results posted
• A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and ChildrenCompletedNCT00468858Phase 2Results posted
• A Phase I/II Trial of a Tetravalent Live Attenuated Dengue Vaccine in Flavivirus Antibody Naïve ChildrenCompletedNCT00384670Phase 1/2Results posted
• A Phase II Trial of a Live Attenuated Virus Tetravalent Dengue Vaccine in Healthy Adults in ThailandCompletedNCT00370682Phase 2Results posted
• Safety and Immunogenicity of Various Formulations of Live Attenuated Tetravalent Dengue Vaccine in Healthy US AdultsCompletedNCT00350337Phase 2Results posted
• A Phase I/II Trial of Tetravalent Live Attenuated Dengue Vaccine in Flavivirus Antibody Naive InfantsCompletedNCT00322049Phase 1/2Results posted
• Safety and Immunogenicity Study of a Dengue Virus DNA VaccineCompletedNCT00290147Phase 1Results posted
• Comparison of Tetravalent Dengue Virus Purified Inactivated Vaccine and Tetravalent Dengue Virus Live Attenuated VaccineStatus unknownNCT03141138Phase 1
• TDENV PIV and LAV Dengue Prime-boost Strategy Using AS03B AdjuvantWithdrawnNCT03110952Phase 1
• Study of Varying Injection Schedules of TDENV-PIV Vaccine With AS03B Adjuvant and Placebo in Healthy US AdultsCompletedNCT02421367Phase 1/2
• Assessment of a Dengue-1-Virus-Live Virus Human Challenge - (DENV-1-LVHC) Virus StrainCompletedNCT02372175Phase 1
• TDENV PIV and LAV Dengue Prime-boost StrategyCompletedNCT02239614Phase 1
• A Two-dose Primary Vaccination Study of a Tetravalent Dengue Virus Purified Inactivated Vaccine vs. Placebo in Healthy Adults (in Puerto Rico)CompletedNCT01702857Phase 1
• Safety Study of a Vaccine (DENV-1 PIV) to Prevent Dengue DiseaseCompletedNCT01502735Phase 1
• Evaluation of the Safety and the Ability of a DNA Vaccine to Protect Against Dengue DiseaseCompletedNCT01502358Phase 1