Takeda: Diabetes Mellitus, Type 2 trials

The registry lists 82 Diabetes Mellitus, Type 2 studies with Takeda as lead sponsor. 0 are open to participants now and 64 have results posted.

Phase 1 4Phase 2 15Phase 3 38Phase 4 8No phase 24(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study for Post-Marketing Surveillance of Nesina® Tablet Monotherapy or Combination Therapy in Participants With Type 2 Diabetes (T2DM) in South KoreaCompletedNCT04980040Results posted
• A Post-Marketing Surveillance Study on NesinaAct® Tablet Use Among Type 2 Diabetes Mellitus Participants in KoreaCompletedNCT04980014Results posted
• Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Severe Renal Impairment or End-stage Renal Disease"CompletedNCT04285983Results posted
• Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus"CompletedNCT03555591Results posted
• Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"CompletedNCT03555565Results posted
• Treatment Preference for Weekly Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Versus Daily DPP-4 Inhibitors in Participants With Type 2 Diabetes MellitusCompletedNCT03231709Phase 4Results posted
• Study of the QOL Evaluation of Trelagliptin in Patients With Type 2 Diabetes MellitusCompletedNCT03014479Phase 4Results posted
• Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical PracticeTerminatedNCT02989649Results posted
• Epidemiologic Study Of Diabetes And Cancer RiskCompletedNCT02958995Results posted
• Cohort Study of Pioglitazone and Cancer Incidence in Participants With Diabetes Mellitus.CompletedNCT02958956Results posted
• Phase 3 Alogliptin Pediatric StudyCompletedNCT02856113Phase 3Results posted
• An Exploratory Study of the Effects of Trelagliptin and Alogliptin on Glucose Variability in Patients With Type 2 Diabetes MellitusCompletedNCT02771093Phase 4Results posted
• An Observational Study of Alogliptin Benzoate in Participants With Diabetes Mellitus Type 2CompletedNCT02756832Results posted
• An Observational Study of Patient Cohorts Who Previously Received Long-term Treatment With Pioglitazone or Placebo in Addition to Existing Antidiabetic MedicationsCompletedNCT02678676Results posted
• Azilsartan Medoxomil in the Treatment of Essential Hypertension and Type 2 Diabetes in AsiaCompletedNCT02517866Phase 4Results posted
• A Phase 3, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 3, Multicenter, Open-label, Long-term Study of SYR-472 (25 mg) in Patients With Type 2 Diabetes Mellitus Complicated by Severe Renal Impairment or End-stage Renal DiseaseCompletedNCT02512068Phase 3Results posted
• TAK-648 Multiple-Rising Dose Study in Healthy Japanese Participants and Non-Japanese Participants With Type 2 Diabetes MellitusCompletedNCT02430870Phase 1Results posted
• A Phase 2 Dose-finding Study of TAK-272 in Participants With Type 2 Diabetes Mellitus and MicroalbuminuriaCompletedNCT02332824Phase 2Results posted
• A Phase 4, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 4, Open-label, Long-term Study of SYR-472 (100 mg) in Combination With Insulin in Patients With Type 2 DiabetesCompletedNCT02324569Phase 3Results posted
• Alogliptin Tablets Specified Drug-use Survey "Type 2 Diabetic Patients Receiving Combination Therapy With a Hypoglycemic Agent (e.g., Insulin Preparations or Rapid-acting Insulin Secretagogues)"CompletedNCT02221284Results posted
• Pioglitazone Tablets Specified Drug-use Survey <Survey on Glycemic Control in Type 2 Diabetic Patients With a History of Cerebral Infarction>CompletedNCT02181842Results posted
• Pioglitazone/Glimepiride (Sonias) Combination Tablets Special Drug Use Surveillance Survey in Patients With Type 2 Diabetes Mellitus Who Respond Poorly to PioglitazoneCompletedNCT02098746Results posted
• Long-term Use of Sonias Combination Tablets in Patients With Type 2 Diabetes MellitusCompletedNCT02098733Results posted
• A Study to Explore the Effects of Azilsartan Compared to Telmisartan on Insulin Resistance of Patients With Essential Hypertension on Type 2 Diabetes Mellitus by HOMA-RCompletedNCT02079805Phase 4Results posted
• Pioglitazone Tablets Special Drug Use Surveillance "Combined Use of Insulin Products / Long-term Treatment"CompletedNCT02068508Results posted
• Comparative Study to Evaluate Efficacy and Safety When Metformin Hydrochloride 500 mg Once Daily is Added on to SYR-322 25 mg in Type 2 Diabetic Patients With Inadequate Glycemic Control Despite Treatment With SYR-322 25 mg in Addition to Diet and Exercise TherapyCompletedNCT02068443Phase 3Results posted
• Efficacy and Safety of Voglibose Compared With Acarbose in Participants With Type 2 DiabetesCompletedNCT02049814Phase 4Results posted
• Special Drug Use Surveillance of Pioglitazone/Metformin Hydrochloride Combination Tablets Survey on Long-term Use for Type 2 Diabetes MellitusCompletedNCT02024971Results posted
• Pioglitazone Tablets Special Drug Use Surveillance "Combined Use of Biguanides / Long-term Treatment"CompletedNCT02003014Results posted
• Pioglitazone Special Drug Use Surveillance "Metabolic Syndrome in Patients With Type 2 Diabetes Mellitus"CompletedNCT02002975Results posted
• Alogliptin/Pioglitazone (Liovel) Combination Tablets Survey on Long-term Use in Patients With Type 2 Diabetes MellitusCompletedNCT01990300Results posted
• Fasiglifam 25 mg BID vs 50 mg QDTerminatedNCT01982253Phase 2Results posted
• Efficacy of Pioglitazone in Participants With Inadequately Controlled Type 2 Diabetes Mellitus Treated With Stable Triple Oral TherapyCompletedNCT01972724Phase 4Results posted
• Alogliptin Tablets Special Drug Use Surveillance Type 2 Diabetes Mellitus: Combination Therapy With BiguanidesCompletedNCT01964976Results posted
• Alogliptin Tablets Special Drug Use Surveillance: Mild Type 2 Diabetes MellitusCompletedNCT01964963Results posted
• Alogliptin Tablets Special Drug Use Surveillance Type 2 Diabetes Mellitus: Combination Therapy With SulfonylureaCompletedNCT01964950Results posted
• Alogliptin Tablets Special Drug Use Surveillance "Type 2 Diabetes Mellitus: Combination Therapy With Thiazolidinediones"CompletedNCT01945242Results posted
• Alogliptin Tablets Special Drug Use Surveillance "Type 2 Diabetes Mellitus: Monotherapy/Combination Therapy With α-GI"CompletedNCT01945216Results posted
• Comparison of Fasiglifam (TAK-875) With Sitagliptin When Used in Combination With Metformin in Patients With Type 2 DiabetesTerminatedNCT01834274Phase 3Results posted
• Comparison of TAK-875 to Placebo as an Add-on to Glimepiride in Patients With Type 2 DiabetesTerminatedNCT01829477Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Daily Oral TAK-875 25 and 50mg in Asia Pacific Adults With Type 2 DiabetesTerminatedNCT01647542Phase 3Results posted
• Study of TAK-875 in Adults With Type 2 Diabetes and Cardiovascular Disease or Risk Factors for Cardiovascular DiseaseTerminatedNCT01609582Phase 3Results posted
• Efficacy and Safety of TAK-875 Compared to Glimepiride When Used With Metformin in Participants With Type 2 DiabetesTerminatedNCT01481116Phase 3Results posted
• Comparison of TAK-875 (Fasiglifam) With Placebo in Participants With Type 2 DiabetesCompletedNCT01456195Phase 3Results posted
• Long-term Safety Study of Alogliptin Used in Combination With Sulfonylurea or Metformin in Participants With Type 2 Diabetes in JapanCompletedNCT01318135Phase 2/3Results posted
• Long-term Safety Study of Alogliptin Used in Combination With Thiazolidine in Participants With Type 2 Diabetes in JapanCompletedNCT01318122Phase 2/3Results posted
• Efficacy and Safety of Alogliptin Used Combination With Metformin in Participants With Type 2 Diabetes in JapanCompletedNCT01318109Phase 2/3Results posted
• Efficacy and Safety of Alogliptin Used in Combination With Sulfonylurea in Participants With Type 2 Diabetes in JapanCompletedNCT01318083Phase 2/3Results posted
• Efficacy and Safety of Alogliptin Used Combination With Thiazolidine in Participants With Type 2 Diabetes in JapanCompletedNCT01318070Phase 2/3Results posted
• Efficacy and Safety of Alogliptin in Participants With Type 2 DiabetesCompletedNCT01289119Phase 3Results posted
• Long-term Safety Study of Alogliptin Used in Combination With α-glucosidase Inhibitor in Participants With Type 2 Diabetes in JapanCompletedNCT01263509Phase 2/3Results posted
• Long-term Safety Study of Alogliptin in Participants With Type 2 Diabetes in JapanCompletedNCT01263496Phase 2Results posted
• Efficacy and Safety of Alogliptin Used in Combination With α-glucosidase Inhibitor in Participants With Type 2 Diabetes in JapanCompletedNCT01263483Phase 2/3Results posted
• Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes in JapanCompletedNCT01263470Phase 2Results posted
• Efficacy and Safety of Alogliptin Plus Metformin in Patients With Type 2 DiabetesCompletedNCT01023581Phase 3Results posted
• Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary SyndromeCompletedNCT00968708Phase 3Results posted
• Pharmacokinetics, Pharmacodynamics, and Safety of Alogliptin in Children, Adolescents and Adults With Type 2 Diabetes MellitusCompletedNCT00957268Phase 1Results posted
• Efficacy and Safety of Alogliptin Plus Metformin Compared to Glipizide Plus Metformin in Patients With Type 2 Diabetes MellitusCompletedNCT00856284Phase 3Results posted
• Safety and Efficacy Study of Alogliptin on Glycemic Control in Subjects With Type 2 Diabetes.CompletedNCT00755846Phase 2Results posted
• Efficacy and Safety of Alogliptin Compared to Glipizide in Elderly DiabeticsCompletedNCT00707993Phase 3Results posted
• Efficacy of Alogliptin and Pioglitazone in Subjects With Type 2 Diabetes MellitusCompletedNCT00432276Phase 3Results posted
• Efficacy and Safety of Alogliptin Combined With Pioglitazone in Treating Subjects With Type 2 Diabetes Mellitus.CompletedNCT00328627Phase 3Results posted
• Study of Alogliptin Combined With Pioglitazone in Subjects With Type 2 Diabetes MellitusCompletedNCT00286494Phase 3Results posted
• Efficacy Study of Pioglitazone Compared to Glimepiride on Coronary Atherosclerotic Disease Progression in Subjects With Type 2 Diabetes MellitusCompletedNCT00225277Phase 3Results posted
• Safety and Efficacy of Alogliptin in Indian Participants With Type 2 Diabetes MellitusWithdrawnNCT03042325Phase 4
• Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on HemodialysisWithdrawnNCT02015780Phase 3
• Efficacy and Safety of TAK-875 in Combination With Sitagliptin in Participants With Type 2 Diabetes MellitusCompletedNCT01414920Phase 2
• Multiple Ascending Dose Trial of BYK324677 in Healthy VolunteersCompletedNCT01386541Phase 1
• Safety and Tolerability of Pioglitazone-Azilsartan in Subjects With Type 2 DiabetesTerminatedNCT01124656Phase 3
• Efficacy and Safety of TAK-875 in Subjects With Type 2 Diabetes MellitusCompletedNCT01007097Phase 2
• Pharmacokinetics and Pharmacodynamics of TAK-875 in Subjects With Type 2 DiabetesCompletedNCT00949091Phase 1
• Efficacy of Pioglitazone and Glimepiride Combination Therapy in Treating Subjects With Type 2 Diabetes Mellitus.CompletedNCT00770952Phase 3
• Efficacy of Pioglitazone and Insulin in Treating Subjects With Type 2 Diabetes Mellitus and Renal Failure.CompletedNCT00770640Phase 2
• Efficacy of TAK-559 in Treating Subjects With Type 2 Diabetes MellitusCompletedNCT00763022Phase 3
• Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus.TerminatedNCT00762957Phase 3
• Efficacy and Safety Study of TAK-559 in Treating Subjects With Type 2 Diabetes MellitusTerminatedNCT00762684Phase 3
• Study of TAK-559 in Treating Subjects With Type 2 Diabetes MellitusTerminatedNCT00762190Phase 3
• Safety Study of TAK-559 in Treating Subjects With Type 2 Diabetes MellitusTerminatedNCT00762112Phase 3
• Efficacy and Safety of TAK-559 Combined With Glyburide in Treating Subjects With Type 2 Diabetes Mellitus.TerminatedNCT00759720Phase 3
• Efficacy, Safety and Tolerability of Pioglitazone-Azilsartan in Subjects With Type 2 Diabetes MellitusTerminatedNCT00376181Phase 3
• Study to Compare Pioglitazone and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus and DyslipidemiaCompletedNCT00331487Phase 3
• Efficacy of Lapaquistat Acetate in Subjects Currently Treated With Lipid-Lowering Therapy.CompletedNCT00251680Phase 3