Sun Yat-sen University: Rectal Neoplasms trials

The registry lists 36 Rectal Neoplasms studies with Sun Yat-sen University as lead sponsor. 16 are open to participants now and 0 have results posted.

Phase 1 1Phase 2 17Phase 3 6No phase 14(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Radiotherapy Combined With Capeox Chemotherapy, Sintilimab and Suvemcitug in Locally Advanced pMMR Rectal Cancer:a Prospective Clinical TrialNot yet recruitingNCT07774754Phase 2
• Transanal Total Mesorectal Excision vs Robotic Total Mesorectal ExcisionRecruitingNCT07651553Not applicable
• Neoadjuvant Radiotherapy Combined With NALIRIFOX and Adebrelimab in pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Randomized, Phase II Clinical TrialRecruitingNCT07622771Phase 2
• Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal CancerRecruitingNCT07528209Phase 3
• Intraoperative Rectal Lavage to Prevent Local Recurrence After Laparoscopic Mid-to-Low Rectal Cancer Resection: A Multicenter Randomized TrialRecruitingNCT07512232Not applicable
• SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal CancerNot yet recruitingNCT07297030Phase 2
• QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal CancerNot yet recruitingNCT07175636Phase 2
• A Phase ll Study of Neoadjuvant Short-course Radiotherapy Followed by Ivonescimab and Chemotherapy in pMMR/MSS Locally Advanced Rectal CancerNot yet recruitingNCT06919510Phase 2
• Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.RecruitingNCT06911684Phase 2
• Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME)RecruitingNCT06380855
• Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer PatientsRecruitingNCT06043999Not applicable
• The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal CancerRecruitingNCT05984485Phase 3
• Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal CancerRecruitingNCT05980689Phase 2
• Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant RadiotherapyRecruitingNCT05965531Phase 2
• Chemotherapy Combined With High-dose Radiotherapy for Low Rectal Cancer Using MR Guided Linear AcceleratorEnrolling by invitationNCT05338866
• Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term RadiationRecruitingNCT03671252Phase 3
• Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer SurgeryActive, not recruitingNCT07432542Not applicable
• Neoadjuvant Chemoradiotherapy Plus Sintilimab for MSS, Locally Advanced Rectal Cancer-WithdrawnNCT06895577Phase 2
• A Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal CancerCompletedNCT06608537Phase 2
• Transanal Versus Laparoscopic Total Mesorectal Excision: a CohortCompletedNCT05682794
• Tumor Budding in Patients With Colorectal Cancer Under Different MMR StatusCompletedNCT05610592
• MRI Features in Neoadjuvant Treatment Decisions for Patients With Rectal CancerCompletedNCT05609149
• Surgery Alone Versus Neoadjuvant Treatment Followed by Surgery For MRI-defined T3 Mid-low Rectal CancerCompletedNCT05496270
• Change of Circulating Tumor Cells During Laparoscopic or Transanal Endoscopic Surgery for Rectal Cancer.Active, not recruitingNCT05109130
• Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune ScoreStatus unknownNCT04989855Phase 2
• TNT to Increase the Clinical Complete Response Rate for Distal LARCActive, not recruitingNCT03840239Phase 2
• High Dose Radiotherapy for the Treatment of Rectal CancerCompletedNCT03541304
• Transanal Versus Laparoscopic Total Mesorectal Excision For Rectal CancerCompletedNCT02966483Not applicable
• FOLFOX6 Totally Neoadjuvant Chemoradiation Therapy in Locally Advanced Rectal Cancer: A Real World StudyStatus unknownNCT02887313Phase 2
• CONVERT: Neoadjuvant Chemotherapy Alone Versus Preoperative Chemoradiation for Locally Advanced Rectal Cancer PatientsActive, not recruitingNCT02288195Phase 3
• The Feasibility and Safety of No-scar Transanal Total Mesorectal Excision for Rectal CancerCompletedNCT02236884Phase 1/2
• Neoadjuvant FOLFOXIRI Chemotherapy Alone for Locally Advanced Rectal CancerCompletedNCT02217020Phase 2
• Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal CancerActive, not recruitingNCT02031939Phase 3
• Preoporative Bevacizumab, Radiation Therapy, and XELOX Chemotherapy for Locally Advanced Nonmetastatic Rectal CancerStatus unknownNCT01818973Phase 2
• Efficacy and Safety Study of Neoadjuvant in Treating Patients With Resectable Local Recurrent Rectal CancerStatus unknownNCT01271192Not applicable
• Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal CancerStatus unknownNCT01211210Phase 2/3