St. Jude Children's Research Hospital: Rhabdoid Tumor trials

The registry lists 10 Rhabdoid Tumor studies with St. Jude Children's Research Hospital as lead sponsor. 2 are open to participants now and 2 have results posted.

Phase 1 6Phase 2 3Phase 3 1No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing SarcomaRecruitingNCT04901702Phase 1/2
• B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)RecruitingNCT04897321Phase 1
• Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or EpendymomaActive, not recruitingNCT00602667Phase 2Results posted
• Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid TumorCompletedNCT00085202Phase 3Results posted
• Trial of Idasanutlin and Selinexor Therapy for Children With Progressive/Relapsed AT/RT or Extra-CNS Malignant Rhabdoid TumorsWithdrawnNCT05952687Phase 1
• Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS TumorsActive, not recruitingNCT05835687Phase 1
• SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain TumorsCompletedNCT03434262Phase 1
• Phase 2 Study of Alisertib Therapy for Rhabdoid TumorsActive, not recruitingNCT02114229Phase 2
• A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and LymphomasCompletedNCT01625351Phase 1
• Study of Stored Tumor Samples in Young Patients With Brain TumorsTerminatedNCT00897286