St. Jude Children's Research Hospital: Central Nervous System Neoplasms trials

The registry lists 19 Central Nervous System Neoplasms studies with St. Jude Children's Research Hospital as lead sponsor. 3 are open to participants now and 4 have results posted.

Phase 1 7Phase 2 6Phase 3 1No phase 6(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS TumorsRecruitingNCT06528691Phase 2
• Expanded Access [11C] Methionine PET ImagingAvailableNCT05511714
• Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology PatientsRecruitingNCT02530658
• Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or EpendymomaActive, not recruitingNCT00602667Phase 2Results posted
• A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side EffectsCompletedNCT00187226Phase 2Results posted
• Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed GliomaCompletedNCT00124657Phase 1/2Results posted
• Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid TumorCompletedNCT00085202Phase 3Results posted
• Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS TumorsActive, not recruitingNCT05835687Phase 1
• Characterizing Sleep Among Long-term Survivors of Childhood CancerActive, not recruitingNCT05480904
• Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain TumorsCompletedNCT04023669Phase 1
• Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline GliomasCompletedNCT03696355Phase 1
• SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain TumorsCompletedNCT03434262Phase 1
• DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem GliomaCompletedNCT00899834
• Study of Stored Tumor Samples in Young Patients With Brain TumorsTerminatedNCT00897286
• A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid TumorsCompletedNCT00756340Phase 1
• Vandetanib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Diffuse Brainstem GliomaCompletedNCT00472017Phase 1
• Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and LymphomasCompletedNCT00152126Not applicable
• Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain TumorCompletedNCT00004068Phase 2
• Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal TumorCompletedNCT00003211Phase 2