Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: Squamous Cell Carcinoma of Head and Neck trials

The registry lists 10 Squamous Cell Carcinoma of Head and Neck studies with Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins as lead sponsor. 0 are open to participants now and 5 have results posted.

Early Phase 1 1Phase 1 2Phase 2 8(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHNCompletedNCT03878979Phase 2Results posted
• A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC.TerminatedNCT01732640Phase 1/2Results posted
• A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive TractCompletedNCT01697800Phase 2Results posted
• Treatment De-Intensification for Squamous Cell Carcinoma of the OropharynxCompletedNCT01088802Phase 2Results posted
• A Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive TractCompletedNCT00894413Phase 2Results posted
• Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).Active, not recruitingNCT05977907Phase 2
• Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck CaActive, not recruitingNCT04848116Phase 2
• Therapy for High-Risk HPV 16-Positive Oropharynx Cancer PatientsWithdrawnNCT04001413Phase 2
• Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial CancerTerminatedNCT00499733Early Phase 1
• MRX, Radiation, and Chemotherapy for Patients With Resected Squamous Cell Carcinoma of the Head and NeckTerminatedNCT00427102Phase 1