Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: Breast Neoplasms trials

The registry lists 55 Breast Neoplasms studies with Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins as lead sponsor. 4 are open to participants now and 22 have results posted.

Early Phase 1 1Phase 1 5Phase 2 24No phase 26(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Study in Patients With Breast Cancer Leptomeningeal MetastasisRecruitingNCT06638294
• Gut Microbiome, Adverse Effects, and Markers Through MEtabolic ReprogrammingRecruitingNCT06536881Not applicable
• PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBCRecruitingNCT06245889Phase 2
• Cardiometabolic Screening ProgramRecruitingNCT05386719Not applicable
• Adaptive Nutrition and Exercise Weight Loss (A-NEW) StudyCompletedNCT04499950Phase 2Results posted
• Automated Method for Breast Cancer DetectionTerminatedNCT03863522Not applicableResults posted
• Involving Family to Improve Communication in Breast Cancer CareCompletedNCT03283553Not applicableResults posted
• Study of Stereotactic Radiotherapy for Breast CancerTerminatedNCT03043794Phase 2Results posted
• Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent SimvastatinTerminatedNCT02096588Phase 2Results posted
• Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast CancerActive, not recruitingNCT01937117Phase 2Results posted
• DIG-HIF-1 Pharmacodynamic Trial in Newly Diagnosed Operable Breast CancerCompletedNCT01763931Phase 2Results posted
• Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal SymptomsCompletedNCT01194440Phase 2Results posted
• A Study of Vorinostat and Tamoxifen in Newly Diagnosed Breast CancerTerminatedNCT01194427Phase 2Results posted
• Study to Evaluate the Effect of Sulforaphane in Broccoli Sprout Extract on Breast TissueCompletedNCT00982319Phase 2Results posted
• Cyclophosphamide and Vaccine Therapy With or Without Trastuzumab in Treating Patients With Metastatic Breast CancerCompletedNCT00971737Phase 2Results posted
• DNA in Predicting Response After Systemic Therapy in Women With Metastatic Breast CancerCompletedNCT00899548Results posted
• Trastuzumab, Cyclophosphamide, and Vaccine Therapy in Treating Patients With High-Risk or Metastatic Breast CancerCompletedNCT00847171Phase 2Results posted
• Cytokine Expression During Radiation for Breast CancerCompletedNCT00836186Not applicableResults posted
• Carboplatin and Nab-Paclitaxel With or Without Vorinostat in Treating Women With Newly Diagnosed Operable Breast CancerActive, not recruitingNCT00616967Phase 2Results posted
• Trastuzumab, Cyclophosphamide, and an Allogeneic GM-CSF-secreting Breast Tumor Vaccine for the Treatment of HER-2/Neu-Overexpressing Metastatic Breast CancerCompletedNCT00399529Phase 2Results posted
• Simvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast CancerCompletedNCT00354640Phase 2Results posted
• Simvastatin in Preventing a New Breast Cancer in Women at High Risk for a New Breast CancerCompletedNCT00334542Phase 2Results posted
• Spect Analysis of Cardiac Perfusion Changes After Whole Breast/Chest Wall Radiation Therapy With ABCCompletedNCT00321048Not applicableResults posted
• Liposomal Doxorubicin Before Mastectomy in Treating Women With Invasive Breast CancerCompletedNCT00290732Phase 1Results posted
• Partial Breast Irradiation With ChemotherapyCompletedNCT00278109Phase 1/2Results posted
• Capecitabine in Treating Patients With Metastatic Breast CancerCompletedNCT00274768Phase 2Results posted
• SMART-ER: Symptom Monitoring With Patient-reported OutcomesTerminatedNCT05560685Not applicable
• Post-Operative Outcomes of Low Thermal Dissection vs. Traditional ElectrosurgeryCompletedNCT03711916Not applicable
• Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast CancerActive, not recruitingNCT03573648Phase 2
• Cancer, Obesity/Overweight and Insomnia StudyCompletedNCT03542604Not applicable
• Pilot Study to Define the Immune Response Following Cryoablation of Invasive Breast CancerWithdrawnNCT03523299Not applicable
• Transcranial Direct Current Stimulation (tDCS) to Improve Fatigue and Cognitive FunctionCompletedNCT03487601Not applicable
• Determinants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6 (CDK4/6) Inhibitor for HR+ MBCActive, not recruitingNCT03439735Phase 2
• Personalized Molecular Profiling in Cancer Treatment at Johns HopkinsActive, not recruitingNCT02965755Not applicable
• Monitoring Plasma Tumor DNA in Early-Stage Breast CancerCompletedNCT02743910
• Palbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase InhibitorActive, not recruitingNCT02738866Phase 2
• Markers for Predicting Risk of Breast Cancer in Women of Different RacesWithdrawnNCT02574546
• Neoadjuvant Doxorubicin/Cyclophosphamide Followed by Eribulin Chemotherapy (ACE) in Operable HER2-negative Breast CancerWithdrawnNCT02215876Phase 2
• FBnTP Imaging of Breast CancerTerminatedNCT02204462Phase 1
• IMAGE Study: Personalized Molecular Profiling in Cancer Treatment at Johns HopkinsCompletedNCT01939847Not applicable
• Johns Hopkins Breast Cancer Program Hormone Therapy Longitudinal DatabaseCompletedNCT01937052
• Johns Hopkins Breast Cancer Program Longitudinal RepositoryActive, not recruitingNCT01937039
• POWER-remote Weight Loss Program in Early Stage Breast CancerCompletedNCT01871116Not applicable
• Decision Support for Women With Breast CancerTerminatedNCT01447771Not applicable
• Identifying Circulating Breast Cancer Cells in Women With Metastatic Breast CancerCompletedNCT00897338
• Topical Application of Sulforaphane-containing Broccoli Sprout Extracts on Radiation DermatitisCompletedNCT00894712
• Ultrasound Based Localization of Lumpectomy Bed in Anatomical Coordinate SystemCompletedNCT00681304
• Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial CancerTerminatedNCT00499733Early Phase 1
• Liposomal Doxorubicin (Lipo-Dox) in Patients With Brain Metastasis From Breast CancerTerminatedNCT00465673Phase 2
• Effect of Surgery, Radiation Therapy, Chemotherapy, and Hormone Therapy on Biomarkers in Women With Stage I, Stage II, Stage III Breast Cancer, or Ductal Carcinoma In Situ That Can Be Removed By SurgeryCompletedNCT00373191
• Identification of a Screening Tool and Treatment of Lymphedema Secondary to the Management of Breast Cancer StudyTerminatedNCT00282529Not applicable
• Anastrozole in Treating Postmenopausal Women With DCIS or Stage I-III Breast CancerCompletedNCT00244959Phase 2
• Vaccine Therapy With or Without Cyclophosphamide and Doxorubicin in Women With Stage IV Breast CancerCompletedNCT00093834Phase 1
• Docetaxel and Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Breast CancerCompletedNCT00080665Phase 1
• Neoadjuvant Docetaxel in Treating Women With Newly Diagnosed Breast CancerTerminatedNCT00080626Phase 2