Royal Marsden NHS Foundation Trust: Head and Neck Neoplasms trials

The registry lists 17 Head and Neck Neoplasms studies with Royal Marsden NHS Foundation Trust as lead sponsor. 6 are open to participants now and 1 have results posted.

Phase 1 1Phase 2 1Phase 3 2No phase 14(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Single and Combined Modality Trans-Oral Robotic Surgery in Early Oropharyngeal CancerRecruitingNCT05933889
• EVEREST-HN 1: EVolution of a patiEnt-REported Symptom-based Risk Stratification sySTemRecruitingNCT05909020
• IReC-Bio and IReC RegistryNot yet recruitingNCT05885490
• The RESCUE Study: Survival and Functional Outcomes Following Salvage Surgery for RESidual or reCurrent sqUamous cEll Carcinoma of the Head and NeckRecruitingNCT05808920
• Exploratory Study of Early Biomarkers Allowing Dynamic Assessment of Response to Treatment in Cancers of the Head and NeckRecruitingNCT05644457
• Exploratory Study of Clonal Evolution in Cancer for Patients Undergoing Transoral Robotic Surgery for Radiation Exposed Residual/reCurrent Tumours of the Upper Aerodigestive TractRecruitingNCT04671940
• Transoral Robotic Surgery for rECurrent Tumours of the Upper Aerodigestive TractCompletedNCT04673929Results posted
• Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel BiomarkersStatus unknownNCT04242459Phase 1/2
• Gustatory Function Following Radiotherapy to the Head and NeckStatus unknownNCT03738657
• A Phase II Study of Parotid-gland Sparing IMRT in Patients With Midline Tumour of the Head and NeckCompletedNCT02149602
• A Prospective Longitudinal Cohort Study Looking at the Difference in Carotid Intima-medial Thickness Between Irradiated and Unirradiated Carotid Arteries in Patients With Head and Neck CancerStatus unknownNCT02069964
• Phase II Study of Whole or Partial Parotid Sparing Intensity Modulated Radiotherapy in Patients With Head and Neck CancersStatus unknownNCT02068313
• A Cross-sectional Study Looking at the Effect of Radiotherapy on Carotid Intima-medial Thickness in Head and Neck CancerCompletedNCT02060643
• Pain: Screen and TreatStatus unknownNCT01716780Phase 3
• The Physiological Response to Routine Head and Neck Cancer SurgeryCompletedNCT01032096
• Functional Imaging in HNC Undergoing ChemoradiationStatus unknownNCT00837980
• Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced XerostomiaStatus unknownNCT00081029Phase 3