Post Graduate Institute of Medical Education and Research, Chandigarh: Acute-On-Chronic Liver Failure trials

The registry lists 11 Acute-On-Chronic Liver Failure studies with Post Graduate Institute of Medical Education and Research, Chandigarh as lead sponsor. 2 are open to participants now and 0 have results posted.

Phase 1 2Phase 4 2No phase 7(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory AscitesRecruitingNCT05700708
• Immune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLFRecruitingNCT05421351
• Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF)CompletedNCT05700695Phase 1
• 20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced HypotensionStatus unknownNCT05441878Phase 4
• Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Hepatorenal Syndrome-Acute Kidney InjuryStatus unknownNCT05434286
• Goal-Directed Hemostatic Resuscitation Trial in ACLF Induced CoagulopathyCompletedNCT05124041Not applicable
• Volume Resuscitation in Cirrhosis With Sepsis Induced HypotensionCompletedNCT05059795
• Global Coagulation Assessment in Cirrhosis and ACLFCompletedNCT04332484
• Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLFCompletedNCT04238416Phase 1
• Anti-fungal Strategies in Acute-on-Chronic Liver Failure PatientsCompletedNCT04157465Not applicable
• PEG3350 in ACLF With Hepatic EncephalopathyStatus unknownNCT03987893Phase 4